SCHEMBL8208147

SCHEMBL8208147

CC(C)C1=C([Si](NC2CCCCC2)(c2ccccc2)c2ccccc2)CC=C1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
LMNA P02545 3/20 0.33
EPHX1 P07099 2/20 0.33
ALDH1A1 P00352 3/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2C19 P33261 2/20 0.33
KDM4E B2RXH2 2/20 0.33
CYP2C9 P11712 1/20 0.33
SCN1A P35498 1/20 0.32
SCN2A Q99250 1/20 0.32
SCN3A Q9NY46 1/20 0.32
EPHX2 P34913 1/20 0.31
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8220094 0.86 L3MBTL1 (0.35) GAAL3MBTL1LMNAEPHX1ALDH1A1
SCHEMBL8216349 0.82 EPHX2 (0.33) GAAL3MBTL1LMNAEPHX1ALDH1A1
SCHEMBL8209130 0.78 NPC1 (0.35) RAB9ASMN1; SMN2
SCHEMBL10319439 0.77
SCHEMBL8207319 0.77
SCHEMBL8220099 0.77 LMNA (0.30) LMNA
SCHEMBL8220118 0.76
SCHEMBL8215565 0.75 CNR2 (0.37) GAAEPHX1EPHX2
SCHEMBL10320071 0.73
SCHEMBL8217606 0.72 LMNA (0.34) GAAL3MBTL1LMNAKDM4EEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6136995-A Process for producing aminosilane compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-24 US disclosed