Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28166421 | 0.80 | LMNA (0.42) | PIK3CDHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL28606988 | 0.77 | PIK3CD (0.39) | PIK3CDHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL26065339 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL489812 | 0.76 | ALDH1A1 (0.52) | HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL821565 | 0.75 | — | — | |
| SCHEMBL5712403 | 0.75 | MAPT (0.42) | PRKCACHRM1TBXA2R | |
| SCHEMBL5987577 | 0.73 | TSHR (0.39) | PIK3CDCHRM1TBXA2R | |
| SCHEMBL11783608 | 0.73 | — | — | |
| SCHEMBL110032 | 0.71 | — | — | |
| SCHEMBL5987581 | 0.71 | PIK3CD (0.39) | PIK3CDCHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110287102-A1 | CHAIN EXTENDERS | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2011-11-24 | — | — | US | disclosed |
| US-20110287102-A1 | CHAIN EXTENDERS | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287102-A1 | CHAIN EXTENDERS | UMPS, PUF60, SMCHD1 | PIK3CD 1868/4885PRKCA 2539/4885HMGCR 1688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.