SCHEMBL8215767

SCHEMBL8215767

Cc1ccccc1C=Cc1cccc(C=Cc2ccccc2C)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.56
KDM4E B2RXH2 1/20 0.56
APOBEC3A P31941 1/20 0.56
APOBEC3G Q9HC16 1/20 0.56
NFE2L2 Q16236 4/20 0.47
TSHR P16473 2/20 0.46
ALDH1A1 P00352 1/20 0.46
PTGS1 P23219 4/20 0.46
PTGS2 P35354 4/20 0.46
CHAT P28329 1/20 0.46
MEN1 O00255 1/20 0.46
PABPC1 P11940 1/20 0.46
KMT2A Q03164 1/20 0.46
ALOX5 P09917 3/20 0.44
NR1H3 Q13133 2/20 0.44
TTR P02766 1/20 0.44
TP53 P04637 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
THPO P40225 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16105507 0.90 PTGS1 (0.58) RAB9AKDM4EAPOBEC3AAPOBEC3GNFE2L2
SCHEMBL16105509 0.90 PTGS1 (0.58) RAB9AKDM4EAPOBEC3AAPOBEC3GNFE2L2
SCHEMBL16105510 0.90 PTGS1 (0.58) RAB9AKDM4EAPOBEC3AAPOBEC3GNFE2L2
SCHEMBL4171932 0.87 APP (0.51) RAB9AKDM4EAPOBEC3AAPOBEC3GNFE2L2
SCHEMBL4171925 0.87 APP (0.51) RAB9AKDM4EAPOBEC3AAPOBEC3GNFE2L2
SCHEMBL4180021 0.87 APP (0.51) RAB9AKDM4EAPOBEC3AAPOBEC3GNFE2L2
SCHEMBL1128126 0.86 RAB9A (0.66) RAB9AKDM4EAPOBEC3AAPOBEC3GNFE2L2
SCHEMBL1128128 0.86 RAB9A (0.66) RAB9AKDM4EAPOBEC3AAPOBEC3GNFE2L2
SCHEMBL16105782 0.86 RAB9A (0.66) RAB9AKDM4EAPOBEC3AAPOBEC3GNFE2L2
SCHEMBL5146541 0.85 RELA (0.56) RAB9AKDM4EAPOBEC3AAPOBEC3GNFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998021521-A9 TWO-PHOTON OR HIGHER-ORDER ABSORBING OPTICAL MATERIALS AND METHODS OF USE CALIFORNIA INST OF TECHN (US) 2000-03-02 WO disclosed
WO-1998021521-A1 TWO-PHOTON OR HIGHER-ORDER ABSORBING OPTICAL MATERIALS AND METHODS OF USE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1998-05-22 WO disclosed