SCHEMBL4171932

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4171925	1.00	APP (0.51)	APPRAB9AKDM4EAPOBEC3AAPOBEC3G
	SCHEMBL4180021	1.00	APP (0.51)	APPRAB9AKDM4EAPOBEC3AAPOBEC3G
	SCHEMBL8215767	0.87	RAB9A (0.56)	RAB9AKDM4EAPOBEC3AAPOBEC3GNFE2L2
	SCHEMBL16105510	0.81	PTGS1 (0.58)	RAB9AKDM4EAPOBEC3AAPOBEC3GNFE2L2
	SCHEMBL4180631	0.81	APP (0.55)	APPNFE2L2PTGS1PTGS2ALOX5
	SCHEMBL698737	0.81	APP (0.55)	APPNFE2L2TRPA1
	SCHEMBL4180629	0.81	APP (0.55)	APPNFE2L2PTGS1PTGS2ALOX5
	SCHEMBL16105507	0.81	PTGS1 (0.58)	RAB9AKDM4EAPOBEC3AAPOBEC3GNFE2L2
	SCHEMBL698738	0.81	APP (0.55)	APPNFE2L2TRPA1
	SCHEMBL8801250	0.81	APP (0.55)	APPNFE2L2PTGS1PTGS2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.