Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8218467 | 0.84 | OPRK1 (0.38) | HPGDRECQLADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL8214038 | 0.81 | KCNH2 (0.48) | HPGDMEN1KMT2AADRB2ADRB1 | |
| SCHEMBL8213885 | 0.81 | RORC (0.41) | HPGDMEN1KMT2ACYP2D6OPRM1 | |
| SCHEMBL7699534 | 0.80 | KEAP1 (0.42) | HPGDRECQLADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL7705359 | 0.69 | KCNH2 (0.46) | HPGDADRB2ADRB1ADRB3CYP2D6 | |
| Hydrochloric Acid SCHEMBL8216596 | 0.68 | KCNH2 (0.50) | HPGDADRB2ADRB1ADRB3CYP2D6 | |
| SCHEMBL7696108 | 0.66 | OPRK1 (0.42) | HPGDRECQLADRB2ADRB1ADRB3 | |
| SCHEMBL14818021 | 0.66 | HPGD (0.46) | HPGDMEN1KMT2A | |
| SCHEMBL5842450 | 0.65 | HPGD (0.63) | HPGDRECQLKDM4EALDH1A1LMNA | |
| SCHEMBL4149990 | 0.64 | HPGD (0.61) | HPGDRECQLKEAP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037871-A1 | NOVEL ANTIARRHYTHMIC COMPOUNDS | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999029655-A1 | NOVEL ANTIARRHYTHMIC COMPOUNDS | Gyógyszerkutató Intézet Kft. (HU) | 1999-06-17 | — | — | WO | disclosed |