Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 15/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.43 |
| ▸ | FAP | Q12884 | 3/20 | 0.41 |
| ▸ | PREP | P48147 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8211698 | 0.92 | DPP4 (0.46) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL8219812 | 0.89 | DPP4 (0.42) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL4801659 | 0.80 | DPP4 (0.48) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL8218015 | 0.80 | DPP4 (0.48) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL4726747 | 0.72 | DPP4 (0.60) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL4726746 | 0.72 | DPP4 (0.60) | DPP4DPP7DPP8DPP9FAP | |
| Hydrochloric Acid SCHEMBL4728792 | 0.71 | LTA4H (0.47) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL8216131 | 0.70 | DPP4 (0.48) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL8219658 | 0.70 | DPP4 (0.48) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL4781929 | 0.70 | DPP4 (0.48) | DPP4DPP7DPP8DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029217-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2008-03-13 | — | — | WO | disclosed |