Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 5/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8216230 | 1.00 | SLC15A1 (0.47) | SLC15A1HSD17B10CTSKCTSBALDH1A1 | |
| SCHEMBL27556472 | 0.88 | SLC15A1 (0.58) | SLC15A1HSD17B10CTSKCTSBALDH1A1 | |
| SCHEMBL27556474 | 0.88 | SLC15A1 (0.58) | SLC15A1HSD17B10CTSKCTSBALDH1A1 | |
| SCHEMBL8209349 | 0.84 | SLC15A1 (0.43) | SLC15A1ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL8209351 | 0.84 | SLC15A1 (0.43) | SLC15A1ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL6576006 | 0.83 | HSD17B10 (0.52) | SLC15A1HSD17B10CTSKCTSBALDH1A1 | |
| SCHEMBL6447818 | 0.82 | MAPT (0.48) | SLC15A1HSD17B10CTSKCTSBALDH1A1 | |
| SCHEMBL8038393 | 0.82 | MAPT (0.48) | SLC15A1HSD17B10CTSKCTSBALDH1A1 | |
| SCHEMBL8219642 | 0.82 | SLC15A1 (0.42) | SLC15A1ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL8219637 | 0.82 | SLC15A1 (0.42) | SLC15A1ALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621270-B1 | Piperazine derivatives as collagenase inhibitors | SANKYO CO (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-5643908-A | ANGIOGENESIS INHIBITOR, ANTITUMOR | SANKYO COMPANY, LIMITED (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0621270-A1 | COLLAGENASE INHIBITOR | SANKYO COMPANY LIMITED (JP) | 1994-10-26 | — | — | EP | disclosed |