Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Hydroxyguanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyguanidine SCHEMBL116225 | 0.85 | — | — | |
| Hydroxyguanidine SCHEMBL7265255 | 0.80 | — | — | |
| Hydroxyguanidine SCHEMBL5262447 | 0.80 | — | — | |
| Guanidine SCHEMBL165720 | 0.74 | NOS2 (0.42) | — | |
| Guanidine SCHEMBL2003 | 0.74 | — | — | |
| Guanidine SCHEMBL29983942 | 0.74 | — | — | |
| Guanidine SCHEMBL5613752 | 0.74 | — | — | |
| Guanidine SCHEMBL11330173 | 0.74 | — | — | |
| Guanidine SCHEMBL687217 | 0.73 | — | — | |
| SCHEMBL2268990 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1007025-A1 | USE OF HYDROXYGUANIDINES | Wa Pharm AB (SE) | 2000-06-14 | — | — | EP | disclosed |
| WO-1998023267-A1 | USE OF HYDROXYGUANIDINES | WAPHARM AB (SE) | 1998-06-04 | — | — | WO | disclosed |