Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.60 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | MMP14 | P50281 | 1/20 | 0.52 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8216687 | 1.00 | LMNA (0.73) | LMNASMN1; SMN2APOBEC3AAPOBEC3GMAPT | |
| SCHEMBL8216684 | 1.00 | LMNA (0.73) | LMNASMN1; SMN2APOBEC3AAPOBEC3GMAPT | |
| SCHEMBL14181813 | 0.87 | MAPT (0.58) | LMNASMN1; SMN2APOBEC3AAPOBEC3GMAPT | |
| SCHEMBL10708397 | 0.83 | MEN1 (0.74) | LMNASMN1; SMN2APOBEC3AAPOBEC3GMAPT | |
| SCHEMBL10708392 | 0.83 | MEN1 (0.74) | LMNASMN1; SMN2APOBEC3AAPOBEC3GMAPT | |
| SCHEMBL13846901 | 0.82 | POLB (0.54) | LMNASMN1; SMN2APOBEC3AAPOBEC3GMAPT | |
| SCHEMBL9580913 | 0.80 | MAPT (0.57) | LMNASMN1; SMN2APOBEC3AAPOBEC3GMAPT | |
| SCHEMBL12136814 | 0.80 | LMNA (0.73) | LMNASMN1; SMN2APOBEC3AAPOBEC3GMAPT | |
| SCHEMBL7690121 | 0.74 | GAA (0.59) | LMNASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL7690119 | 0.74 | GAA (0.59) | LMNASMN1; SMN2MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188130-B1 | Anti-cancer hydantoin compounds and methods | UNIVERSITY OF LOUISIANA AT MONROE (US) | 2012-05-29 | — | — | US | claimed |
| US-8188130-B1 | Anti-cancer hydantoin compounds and methods | UNIVERSITY OF LOUISIANA AT MONROE (US) | 2012-05-29 | — | — | US | disclosed |