Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.67 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | GSK3B | P49841 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | CLK1 | P49759 | 1/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | NAT1 | P18440 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10708392 | 1.00 | MEN1 (0.74) | MEN1KMT2AGAAPOLBNCOA1 | |
| SCHEMBL10709993 | 0.86 | MEN1 (0.72) | MEN1KMT2AGAAPOLBNCOA1 | |
| SCHEMBL14586372 | 0.85 | NPC1 (0.68) | MEN1KMT2AGAAPOLBNCOA1 | |
| SCHEMBL9255656 | 0.84 | MMP2 (0.64) | MEN1KMT2AGAAPOLBNCOA1 | |
| SCHEMBL9255652 | 0.84 | MMP2 (0.64) | MEN1KMT2AGAAPOLBNCOA1 | |
| SCHEMBL8216684 | 0.83 | LMNA (0.73) | MEN1KMT2AGAAPOLBNCOA1 | |
| SCHEMBL8216686 | 0.83 | LMNA (0.73) | MEN1KMT2AGAAPOLBNCOA1 | |
| SCHEMBL8216687 | 0.83 | LMNA (0.73) | MEN1KMT2AGAAPOLBNCOA1 | |
| SCHEMBL6673005 | 0.81 | NPC1 (0.55) | MEN1KMT2AGAAPOLBNCOA1 | |
| SCHEMBL15421799 | 0.80 | POLB (0.79) | MEN1KMT2AGAAPOLBNCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800921-B | Imidazolidine diketone HDAC inhibitor, preparation method and application | 南京市鸿舜医药科技有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-117800921-A | Imidazolidine diketone HDAC inhibitor, preparation method and application | 南京市鸿舜医药科技有限公司 | 2024-04-02 | — | — | CN | disclosed |
| EP-0156582-B1 | PROCESS FOR THE PREPARATION OF DL-BETA-ARYL AMINO ACIDS | ALKALOIDA VEGYESZETI GYAR (HU) | 1988-09-14 | — | — | EP | disclosed |
| US-4647694-A | Process for the preparation of D1-β-aryl amino acids | ALKALOIDA VEGYESZETI GYAR (HU) | 1987-03-03 | — | — | US | disclosed |
| US-4264617-A | VIRICIDES, VETERNARY MEDICINE | CANADA PACKERS, LIMITED (CA) | 1981-04-28 | — | — | US | disclosed |
| US-4065571-A | Antiviral 5-(substituted benzal) hydantoins | CANADA PACKERS LIMITED (CA) | 1977-12-27 | — | — | US | disclosed |
| US-4065570-A | Antiviral 5-(substituted benzal) hydantoins | CANADA PACKERS LIMITED (CA) | 1977-12-27 | — | — | US | disclosed |
| US-4013770-A | PICORNA VIRUSES | CANADA PACKERS LIMITED (CA) | 1977-03-22 | — | — | US | disclosed |