Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8218550 | 0.91 | THRB (0.38) | MAPK1HIF1AHTT | |
| SCHEMBL26832067 | 0.89 | ALDH1A1 (0.39) | MAPK1HIF1AHTTALDH1A1TP53 | |
| SCHEMBL8208674 | 0.84 | SERPINE1 (0.36) | HTTMMP8TSHRCYP3A4HSD17B10 | |
| SCHEMBL3443441 | 0.84 | LMNA (0.32) | HTTMMP8TSHRCYP3A4HSD17B10 | |
| SCHEMBL13851193 | 0.82 | THRB (0.37) | MAPK1HIF1AALDH1A1TSHRTP53 | |
| SCHEMBL8308167 | 0.82 | HTT (0.56) | HTTALDH1A1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL6367508 | 0.82 | LMNA (0.31) | HTTMMP8TSHRCYP3A4HSD17B10 | |
| SCHEMBL27280920 | 0.82 | CHRM2 (0.33) | HTT | |
| SCHEMBL8219523 | 0.82 | SMN1; SMN2 (0.41) | MAPK1HIF1AHTTALDH1A1TSHR | |
| SCHEMBL18674552 | 0.80 | HTT (0.39) | HTTMMP8HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580308-B1 | Working fluid composition for refrigeration machine | KAO CORP (JP) | 2000-11-15 | — | — | EP | disclosed |
| US-5395544-A | Ester-containing working fluid composition for refrigerating machine | KAO CORPORATION (JP) | 1995-03-07 | — | — | US | disclosed |
| EP-0580308-A1 | Working fluid composition for refrigeration machine | KAO CORPORATION (JP) | 1994-01-26 | — | — | EP | disclosed |