Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MMP14 | P50281 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.38 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.38 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112230 | 0.83 | KMT2A (0.55) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL29358253 | 0.83 | KMT2A (0.55) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL112231 | 0.83 | KMT2A (0.55) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL10067503 | 0.81 | KMT2A (0.50) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL9307057 | 0.80 | MAPT (0.51) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL9307054 | 0.80 | MAPT (0.51) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL25419671 | 0.78 | KMT2A (0.47) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL9717137 | 0.78 | TSHR (0.49) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL8216589 | 0.77 | MAPT (0.49) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL8216588 | 0.77 | MAPT (0.49) | MAPTMEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0992832-A1 | Optical element for use in eye-protecting devices | INTERCAST EUROPE S.P.A. (IT) | 2000-04-12 | — | — | EP | disclosed |
| US-5975695-A | Optical element for use in eye-protecting devices | INTERCAST EUROPE S.P.A. (IT) | 1999-11-02 | — | — | US | disclosed |