Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL538592 | 0.84 | ALDH1A1 (0.46) | ALOX5APFEN1MMP1MMP2MMP3 | |
| SCHEMBL10799367 | 0.82 | PTGS1 (0.45) | ALOX5APFEN1MMP1MMP2MMP3 | |
| SCHEMBL8617339 | 0.80 | GSTP1 (0.57) | NPC1CYP1A2MAPTCYP2C19SMN1; SMN2 | |
| SCHEMBL6687063 | 0.79 | ALOX5AP (0.43) | ALOX5APFEN1MMP1MMP2MMP3 | |
| SCHEMBL8613447 | 0.79 | MAOB (0.55) | MAPTMAPK1 | |
| SCHEMBL8617910 | 0.79 | GSTP1 (0.56) | NPC1CYP1A2MAPTCYP2C19SMN1; SMN2 | |
| SCHEMBL8615440 | 0.78 | GSTP1 (0.55) | ALOX5APFEN1ARNPC1CYP1A2 | |
| SCHEMBL6684291 | 0.77 | RARB (0.48) | ALOX5APFEN1MMP1MMP2MMP3 | |
| SCHEMBL5553086 | 0.77 | ALOX5AP (0.41) | ALOX5APFEN1MMP1MMP2MMP3 | |
| SCHEMBL8218707 | 0.76 | MGLL (0.42) | CALM1MEN1KMT2APDK2IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013197-A | POLYMERIZABLE, MONO- OR DI-REACTIVE LIQUID CRYSTAL WITH DIFFERENT CORE GROUPS; LOW MELTING POINT AND WIDE LIQUID CRYSTAL PHASE RANGE, PARTICULARLY NEMATIC; USE IN INTEGRATED OPTICS, OPTOELECTRONICS OR INFORMATION STORAGE COMPONENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-01-11 | — | — | US | disclosed |
| US-5720900-A | PHOTOPOLYMERIZABLE ACRYLATE ESTERS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-02-24 | — | — | US | disclosed |
| US-5518652-A | PREPARED BY IN SITU PHOTOPOLYMERIZATION | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-05-21 | — | — | US | disclosed |