SCHEMBL10799367

SCHEMBL10799367

Fc1cc(Br)ccc1-c1ccccc1.[MgH2]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 3/20 0.45
LMNA P02545 3/20 0.45
MEN1 O00255 2/20 0.45
PTGS2 P35354 2/20 0.45
KMT2A Q03164 2/20 0.45
HPGD P15428 2/20 0.45
FABP2 P12104 1/20 0.45
TSHR P16473 1/20 0.45
AKR1C4 P17516 1/20 0.45
ADRA2B P18089 1/20 0.45
CHRM3 P20309 1/20 0.45
HTR2C P28335 1/20 0.45
DRD3 P35462 1/20 0.45
AKR1C3 P42330 1/20 0.45
AKR1C2 P52895 1/20 0.45
AKR1C1 Q04828 1/20 0.45
SLC22A6 Q4U2R8 1/20 0.45
CYP1A2 P05177 1/20 0.45
MAPT P10636 1/20 0.45
CYP2C9 P11712 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL538592 0.98 ALDH1A1 (0.46) PTGS1LMNAMEN1PTGS2KMT2A
SCHEMBL2010580 0.87 MMP1 (0.47) PTGS1LMNAMEN1PTGS2KMT2A
SCHEMBL8216773 0.82 ALOX5AP (0.41) MEN1KMT2ACYP1A2MAPTCYP2C9
SCHEMBL8951029 0.82 ALOX5AP (0.46) PTGS1LMNAMEN1PTGS2KMT2A
SCHEMBL10269866 0.81 ALOX5AP (0.49) PTGS1LMNAMEN1PTGS2KMT2A
SCHEMBL28462601 0.81 MAPK1 (0.46) LMNAMEN1KMT2AHPGDAKR1C3
SCHEMBL10269901 0.80 ALOX5AP (0.45) HPGDMAPTALOX5APFEN1NMUR2
SCHEMBL31010675 0.80 L3MBTL1 (0.41) MEN1KMT2AHPGDTSHRCYP1A2
SCHEMBL14520998 0.79 DGAT1 (0.46) LMNAHPGDALDH1A1ALOX5APFEN1
SCHEMBL31310573 0.79 DGAT1 (0.46) LMNAHPGDALDH1A1ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120463591-A Preparation method of low-cost high-purity flurbiprofen 云南省药物研究所 2025-08-12 CN disclosed
US-4695131-A FLUORINATED AROMATIC COMPOUNDS; INSTRUMENT PANELS, AUTOMOBILES QINETIQ LIMITED (GB) 1987-09-22 US disclosed
EP-0117631-B1 DISUBSTITUTED ETHANES AND THEIR USE IN LIQUID CRYSTAL MATERIALS AND DEVICES The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1987-04-29 EP disclosed
US-4518799-A GRIGNARD REAGENTS AND THEIR PREPARATION THE UPJOHN COMPANY (US) 1985-05-21 US disclosed
EP-0117631-A1 Disubstituted ethanes and their use in liquid crystal materials and devices The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1984-09-05 EP disclosed
US-4443631-A DIMETHYLFORMAMIDE OR DIMETHYLACETAMIDE SOLVENT 2-(2-FLUORO-4-BIPHENYLYL)PROPIONIC ACID INTERMEDIATE THE UPJOHN COMPANY (US) 1984-04-17 US disclosed