Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.42 |
| ▸ | MTOR | P42345 | 3/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8219069 | 0.88 | KLKB1 (0.44) | KLKB1RAB9ANPC1EPHX1GAA | |
| SCHEMBL8219738 | 0.83 | EPHX1 (0.42) | KLKB1PIK3CAMTORPIK3CGRAB9A | |
| SCHEMBL8212700 | 0.83 | KLKB1 (0.44) | KLKB1PIK3CAMTORPIK3CGRAB9A | |
| SCHEMBL8214361 | 0.80 | PIK3CA (0.47) | KLKB1PIK3CAMTORPIK3CGRAB9A | |
| SCHEMBL8219731 | 0.80 | KLKB1 (0.42) | KLKB1PIK3CAMTORRAB9ANPC1 | |
| SCHEMBL8212640 | 0.80 | PIK3CA (0.51) | KLKB1PIK3CAMTORRAB9ANPC1 | |
| SCHEMBL8213959 | 0.79 | PIK3CA (0.48) | PIK3CAMTORPIK3CGKDREPHX2 | |
| SCHEMBL11925988 | 0.79 | RAB9A (0.52) | RAB9ANPC1EPHX1GAAKDR | |
| SCHEMBL8217151 | 0.78 | EPHX2 (0.43) | KLKB1PIK3CAMTORPIK3CGRAB9A | |
| SCHEMBL8217175 | 0.78 | EPHX2 (0.47) | PIK3CAMTORPIK3CGRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008023159-A1 | MORPHOLINO PYRIMIDINE DERIVATIVES USEFUL IN THE TREATMENT OF PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2008-02-28 | — | — | WO | disclosed |