Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | GFER | P55789 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 4/20 | 0.59 |
| ▸ | CA2 | P00918 | 4/20 | 0.59 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.59 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.59 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.59 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.59 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.59 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2599799 | 0.98 | RAB9A (0.70) | RAB9ANPC1KMT2AMAPTGFER | |
| SCHEMBL738324 | 0.98 | RAB9A (0.70) | RAB9ANPC1KMT2AMAPTGFER | |
| SCHEMBL1862570 | 0.98 | RAB9A (0.70) | RAB9ANPC1KMT2AMAPTGFER | |
| Hydrochloric Acid SCHEMBL7329333 | 0.96 | RAB9A (0.68) | RAB9ANPC1KMT2AMAPTGFER | |
| Hydrochloric Acid SCHEMBL7329327 | 0.96 | RAB9A (0.68) | RAB9ANPC1KMT2AMAPTGFER | |
| SCHEMBL6076687 | 0.81 | ALDH1A1 (0.61) | RAB9ANPC1KMT2AMAPTALDH1A1 | |
| SCHEMBL6076692 | 0.81 | ALDH1A1 (0.61) | RAB9ANPC1KMT2AMAPTALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL7284354 | 0.81 | KMT2A (0.55) | RAB9ANPC1KMT2AMAPTGFER | |
| SCHEMBL19439618 | 0.80 | ALDH1A1 (0.59) | RAB9ANPC1KMT2AMAPTALDH1A1 | |
| SCHEMBL13934092 | 0.80 | CA2 (0.88) | RAB9ANPC1MAPTALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020334-A | Piperazinones, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-02-01 | — | — | US | disclosed |