Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.38 |
| ▸ | CHRNG | P07510 | 3/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.38 |
| ▸ | CHRND | Q07001 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8215573 | 0.90 | SLC6A4 (0.46) | CCR2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8218564 | 0.90 | SLC6A4 (0.46) | CCR2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL4728513 | 0.90 | SLC6A4 (0.46) | CCR2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL18346500 | 0.74 | CCR2 (0.39) | CCR2SLC6A4SLC6A3SLC6A2MCL1 | |
| SCHEMBL18346498 | 0.74 | CCR2 (0.39) | CCR2SLC6A4SLC6A3SLC6A2MCL1 | |
| SCHEMBL18346492 | 0.74 | CCR2 (0.39) | CCR2SLC6A4SLC6A3SLC6A2MCL1 | |
| SCHEMBL14255658 | 0.73 | SLC6A3 (0.45) | CCR2SLC6A4SLC6A3SLC6A2CYP3A4 | |
| SCHEMBL8216816 | 0.73 | SLC6A3 (0.45) | CCR2SLC6A4SLC6A3SLC6A2CYP3A4 | |
| SCHEMBL8208270 | 0.73 | SLC6A3 (0.45) | CCR2SLC6A4SLC6A3SLC6A2CYP3A4 | |
| SCHEMBL29302948 | 0.71 | KDM4E (0.40) | L3MBTL1SMN1; SMN2MAPTALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008013856-A2 | METHODS AND COMPOSITIONS FOR PRODUCTION, FORMULATION AND USE OF 1 ARYL -3-AZABICYCLO[3.1.0 ] HEXANES | DOV PHARMACEUTICAL, INC. (US) | 2008-01-31 | — | — | WO | disclosed |