Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A11 | P48066 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | PRKDC | P78527 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31358816 | 0.78 | ADORA1 (0.55) | SLC6A11KCNH2PGRADORA1SRD5A1 | |
| SCHEMBL2238249 | 0.78 | ADORA1 (0.55) | SLC6A11KCNH2PGRADORA1SRD5A1 | |
| SCHEMBL4243227 | 0.77 | SLC6A11 (0.48) | SLC6A11KCNH2PGRADORA1SRD5A1 | |
| SCHEMBL30512416 | 0.76 | SLC6A11 (0.61) | SLC6A11KCNH2PGRERN1PDK2 | |
| SCHEMBL21580251 | 0.76 | SLC6A11 (0.61) | SLC6A11KCNH2PGRERN1PDK2 | |
| SCHEMBL14322894 | 0.76 | PDK2 (0.52) | SLC6A11KCNH2ADORA1ERN1PDK2 | |
| SCHEMBL15571040 | 0.74 | CLK4 (0.60) | SLC6A11KCNH2PGRERN1PDK2 | |
| SCHEMBL27554974 | 0.73 | SLC6A11 (0.58) | SLC6A11KCNH2PGRADORA1ERN1 | |
| SCHEMBL3460160 | 0.73 | HSD17B1 (0.53) | SLC6A11KCNH2PGRADORA1SRD5A1 | |
| SCHEMBL8214476 | 0.73 | PTPRC (0.54) | BCHECES1KCNH2ERN1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127189-A | CONTACTING WITH A 1,2-INDANEDIONE DERIVATIVE, MEASURING ABSORBANCE OR FLUORESCENCE OF PRODUCT FORMED, AND COMPARING TO STANDARDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2000-10-03 | — | — | US | claimed |
| WO-1998020344-A1 | COMPOSITIONS AND METHODS FOR DETECTION OF AN AMINE COMPOUND | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1998-05-14 | — | — | WO | claimed |
| US-6127189-A | CONTACTING WITH A 1,2-INDANEDIONE DERIVATIVE, MEASURING ABSORBANCE OR FLUORESCENCE OF PRODUCT FORMED, AND COMPARING TO STANDARDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2000-10-03 | — | — | US | disclosed |
| WO-1998020344-A1 | COMPOSITIONS AND METHODS FOR DETECTION OF AN AMINE COMPOUND | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1998-05-14 | — | — | WO | disclosed |