SCHEMBL2238249

SCHEMBL2238249

c1csc(-c2ccc3c(c2)Cc2cc(-c4cccs4)ccc2-3)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 2/20 0.55
KCNH2 Q12809 1/20 0.53
PDK2 Q15119 1/20 0.50
SLC6A11 P48066 1/20 0.46
LTA4H P09960 1/20 0.46
ERN1 O75460 1/20 0.45
PGR P06401 2/20 0.42
SRD5A1 P18405 1/20 0.42
CYP2E1 P05181 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2A6 P11509 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2B6 P20813 1/20 0.41
PRMT6 Q96LA8 1/20 0.41
CYP17A1 P05093 1/20 0.41
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
ALOX5 P09917 1/20 0.40
PTGS1 P23219 1/20 0.40
PTGS2 P35354 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31358816 1.00 ADORA1 (0.55) ADORA1KCNH2PDK2SLC6A11LTA4H
SCHEMBL14322894 0.93 PDK2 (0.52) ADORA1KCNH2PDK2SLC6A11LTA4H
SCHEMBL1926437 0.81 KCNH2 (0.50) ADORA1KCNH2PDK2SLC6A11LTA4H
SCHEMBL10410607 0.81 KCNH2 (0.50) ADORA1KCNH2PDK2SLC6A11LTA4H
SCHEMBL3460160 0.79 HSD17B1 (0.53) ADORA1KCNH2PDK2SLC6A11ERN1
SCHEMBL8218486 0.78 SLC6A11 (0.52) ADORA1KCNH2PDK2SLC6A11LTA4H
SCHEMBL13291981 0.77 KCNH2 (0.50) ADORA1KCNH2PDK2LTA4HERN1
SCHEMBL15570741 0.77 CLK4 (0.54) KCNH2SLC6A11PGRFLT3
SCHEMBL7505848 0.77 HSD17B1 (0.55) ADORA1KCNH2SLC6A11ERN1PGR
SCHEMBL31070976 0.76 ADORA1 (0.45) ADORA1KCNH2PDK2CYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2536700-B1 SEMICONDUCTING POLYMERS MERCK PATENT GMBH (DE) 2019-10-02 EP claimed
US-9365585-B2 Semiconducting polymers MERCK PATENT GMBH (DE) 2016-06-14 US claimed
US-9212260-B2 Polymers of 8,9-dihydrobenzo[def]carbazole and their use as organic semiconductors MERCK PATENT GMBH (DE) 2015-12-15 US claimed
EP-2631230-B1 Semiconducting Polymers MERCK PATENT GMBH (DE) 2015-01-21 EP claimed
EP-2563836-B1 POLYMERS OF 8,9-DIHYDROBENZO(DEF)CARBAZOLE AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2014-03-26 EP claimed
EP-2631230-A1 Semiconducting Polymers Merck Patent GmbH (DE) 2013-08-28 EP claimed
EP-2563836-A1 POLYMERS OF 8,9-DIHYDROBENZO(DEF)CARBAZOLE AND THEIR USE AS ORGANIC SEMICONDUCTORS Merck Patent GmbH (DE) 2013-03-06 EP claimed
US-20130001476-A1 POLYMERS OF 8,9-DIHYDROBENZO[DEF]CARBAZOLE AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-01-03 US claimed
EP-2536700-A2 SEMICONDUCTING POLYMERS Merck Patent GmbH (DE) 2012-12-26 EP claimed
US-20120305853-A1 SEMICONDUCTING POLYMERS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-12-06 US claimed
WO-2011116866-A1 POLYMERS OF 8,9-DIHYDROBENZO[DEF]CARBAZOLE AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2011-09-29 WO claimed
WO-2011098113-A2 SEMICONDUCTING POLYMERS MERCK PATENT GMBH (DE) 2011-08-18 WO claimed
US-12376485-B2 Self-assembled monolayer for electrode modification and device comprising such self-assembled monolayer MERCK PATENT GMBH (DE) 2025-07-29 US disclosed
EP-3891818-B1 METHOD FOR PRODUCING SELF-ASSEMBLED MONOLAYER FOR ELECTRODE MODIFICATION AND METHOD FOR PRODUCING DEVICE COMPRISING SUCH SELF-ASSEMBLED MONOLAYER MERCK PATENT GMBH (DE) 2025-02-26 EP disclosed
US-20240298522-A1 SELF-ASSEMBLED MONOLAYER FOR ELECTRODE MODIFICATION AND DEVICE COMPRISING SUCH SELF-ASSEMBLED MONOLAYER MERCK PATENT GMBH (DE) 2024-09-05 US disclosed
US-11552266-B2 Electrodes for electronic devices comprising an organic semiconducting layer FLEXENABLE LIMITED (GB) 2023-01-10 US disclosed
US-20120305853-A1 SEMICONDUCTING POLYMERS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-12-06 US disclosed
WO-2011131280-A1 POLYMERS OF BENZODITHIOPHENE AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2011-10-27 WO disclosed
WO-2011116866-A1 POLYMERS OF 8,9-DIHYDROBENZO[DEF]CARBAZOLE AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2011-09-29 WO disclosed
WO-2011098113-A2 SEMICONDUCTING POLYMERS MERCK PATENT GMBH (DE) 2011-08-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130001476-A1 POLYMERS OF 8,9-DIHYDROBENZO[DEF]CARBAZOLE AND THEIR USE AS ORGANIC SEMICONDUCTORS DDT, PPOX, DDO ADORA1 4226/4885KCNH2 1434/4885PDK2 1241/4885
US-20120305853-A1 SEMICONDUCTING POLYMERS PPOX, OCIAD2, OCIAD1 ADORA1 4789/4885KCNH2 1391/4885PDK2 1463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.