Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 15/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3452620 | 0.81 | PDE4B (0.58) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL19155628 | 0.78 | PDE4B (0.54) | PDE4BPDE4D | |
| SCHEMBL4669064 | 0.77 | PDE4B (0.51) | PDE4BPDE4DPDE4APDE4C | |
| Hydrochloric Acid SCHEMBL3451926 | 0.77 | PDE4B (0.51) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6027642 | 0.75 | PDE4D (0.74) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL464942 | 0.74 | PDE4D (0.72) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6725922 | 0.74 | PDE4D (0.72) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL19155555 | 0.74 | PDE4D (0.72) | PDE4BPDE4DPDE4APDE4C | |
| Hydrochloric Acid SCHEMBL4013065 | 0.74 | PDE4D (0.71) | PDE4BPDE4DPDE4APDE4C | |
| Hydrochloric Acid SCHEMBL6031622 | 0.71 | PDE4B (0.49) | PDE4BPDE4DPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008003701-A2 | COMBINATION OF HMG-COA REDUCTASE INHIBITORS WITH PHOSPHODIESTERASE 4 INHIBITORS FOR THE TREATMENT OF INFLAMMATORY PULMONARY DISEASES | NYCOMED GMBH (DE) | 2008-01-10 | — | — | WO | disclosed |