Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28010292 | 0.88 | DRD2 (0.42) | TAAR1SLC6A3KCNH2 | |
| SCHEMBL8182387 | 0.81 | DAGLA (0.41) | TAAR1SLC6A3KCNH2 | |
| SCHEMBL28666083 | 0.80 | DRD2 (0.50) | — | |
| SCHEMBL28105993 | 0.79 | DRD2 (0.42) | — | |
| SCHEMBL28966471 | 0.78 | DRD2 (0.44) | TAAR1 | |
| SCHEMBL29034235 | 0.77 | KDM4E (0.43) | TAAR1SLC6A3KCNH2 | |
| SCHEMBL28029236 | 0.77 | ADRA2C (0.52) | SLC6A3 | |
| SCHEMBL27816652 | 0.76 | DRD2 (0.42) | — | |
| SCHEMBL28257239 | 0.76 | DRD2 (0.43) | — | |
| SCHEMBL1665692 | 0.76 | DRD2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | disclosed |