SCHEMBL27816652

SCHEMBL27816652

Nc1cccnc1C1CNCCO1

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.42
DRD3 P35462 1/20 0.42
PRKACA P17612 1/20 0.41
PRKACG P22612 1/20 0.41
PRKACB P22694 1/20 0.41
HTR1A P08908 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28666083 0.83 DRD2 (0.50) DRD2DRD3
SCHEMBL28105993 0.82 DRD2 (0.42) DRD2DRD3
SCHEMBL28860435 0.81 DRD2 (0.41) DRD2DRD3HTR1A
SCHEMBL28029236 0.79 ADRA2C (0.52) HTR1A
SCHEMBL28257239 0.78 DRD2 (0.43) DRD2DRD3HTR1A
SCHEMBL1665692 0.78 DRD2 (0.40) DRD2DRD3HTR1A
SCHEMBL28010292 0.77 DRD2 (0.42) DRD2DRD3
SCHEMBL8152385 0.77 HTR7 (0.42) DRD2DRD3
SCHEMBL8218635 0.76 TAAR1 (0.44)
SCHEMBL28061366 0.75 APLNR (0.40) DRD2DRD3HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119498317-A Bactericide and preparation method thereof 滨州乾坤化工机械有限公司 2025-02-25 CN claimed
CN-118598857-A Bactericide for oilfield fracturing acidification and preparation method and application thereof 胜利油田物华化工厂 2024-09-06 CN claimed
CN-119498317-A Bactericide and preparation method thereof 滨州乾坤化工机械有限公司 2025-02-25 CN disclosed
WO-2024240242-A1 COMPOUND CONTAINING AMIDE-SUBSTITUTED AROMATIC RING, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 正大天晴药业集团股份有限公司 2024-11-28 WO disclosed
CN-118598857-A Bactericide for oilfield fracturing acidification and preparation method and application thereof 胜利油田物华化工厂 2024-09-06 CN disclosed
CN-117924198-A Bioactive compounds and methods thereof 上海科因生物医药科技有限公司 2024-04-26 CN disclosed
CN-111630030-B Novel benzamide derivatives as PPAR-gamma modulators 梅迪比奥法尔玛公司 2023-06-20 CN disclosed
CN-111630030-A Novel benzamide derivatives as PPAR-gamma modulators 梅迪比奥法尔玛公司 2020-09-04 CN disclosed
CN-110709082-A Methods of use of indazole-3-carboxamides and their use as inhibitors of the Wnt/beta-catenin signaling pathway 萨穆梅德有限公司 2020-01-17 CN disclosed
CN-104910148-A Aminotriazolopyridines and use thereof as kinase inhibitors SIGNAL PHARM LLC 2015-09-16 CN disclosed
CN-104903320-A Nitrogen-containing heterocylic compound or salt thereof FUJIFILM CORP 2015-09-09 CN disclosed
CN-102203093-B Aminotriazolopyridines and their use as kinase inhibitors SIGNAL PHARM LLC 2015-05-13 CN disclosed
CN-104334527-A Sulfonamide compounds and uses as tnap inhibitors SANFORD BURNHAM MED RES INST 2015-02-04 CN disclosed
CN-103492389-A Pyrazolo [4, 3-d] pyrimidines useful as kinase inhibitors ORIGENIS GMBH 2014-01-01 CN disclosed
CN-102203093-A Aminotriazolopyridines and their use as kinase inhibitors SIGNAL PHARM LLC 2011-09-28 CN disclosed
CN-101883774-A Thienopyrimidine and pyrazolopyrimidine compounds and their use as MTOR kinase and PI3 kinase inhibitors WYETH CORP 2010-11-10 CN disclosed