SCHEMBL8218807

SCHEMBL8218807

COC(=O)C(=O)[C@@H](N)CC(=O)O

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 1/20 0.39
TGFBR1 P36897 1/20 0.34
BHMT Q93088 1/20 0.34
SLC1A1 P43005 1/20 0.34
S1PR1 P21453 1/20 0.34
S1PR3 Q99500 1/20 0.34
GABRR1 P24046 2/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
DPP4 P27487 1/20 0.33
DPP8 Q6V1X1 1/20 0.33
DPP9 Q86TI2 1/20 0.33
LMNA P02545 1/20 0.33
GFPT1 Q06210 1/20 0.33
LTA4H P09960 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17921870 0.78 SLC22A6 (0.45) BHMTSLC1A1GABRR1SLC22A6LMNA
SCHEMBL10611199 0.78 SLC7A5 (0.34) BHMTGABRR1SLC22A6LMNA
SCHEMBL6259101 0.77 KMT2A (0.37) BHMTSLC1A1S1PR1S1PR3GABRR1
SCHEMBL416894 0.77 KMT2A (0.37) BHMTSLC1A1S1PR1S1PR3GABRR1
SCHEMBL996039 0.77 KMT2A (0.37) BHMTSLC1A1S1PR1S1PR3GABRR1
SCHEMBL27769181 0.77 SLC1A1 (0.35) EGLN1TGFBR1SLC1A1DPP4DPP8
SCHEMBL27510502 0.77 GRIK1 (0.39) BHMTSLC1A1GABRR1SLC22A6LMNA
SCHEMBL15373385 0.77 TGFBR1 (0.41) EGLN1TGFBR1SLC1A1GFPT1
SCHEMBL126426 0.76 SMN1; SMN2 (0.48) EGLN1TGFBR1GABRR1SLC22A6LMNA
Hydrochloric Acid SCHEMBL4678540 0.76 KMT2A (0.36) BHMTSLC1A1S1PR1S1PR3GABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9526794-B2 Injectable dendrimer hydrogel nanoparticles WAYNE STATE UNIVERSITY (US) 2016-12-27 US disclosed
EP-2369006-B1 Covalent tethering of functional groups to proteins PROMEGA CORP (US) 2014-03-12 EP disclosed
US-6015792-A Specific eatable taste modifiers BIORESEARCH, INC. (US) 2000-01-18 US disclosed
US-6008250-A Specific eatable taste modifiers BIORESEARCH, INC. (US) 1999-12-28 US disclosed
US-5866608-A AROMATIC COMPOUNDS BIORESEARCH, INC. (US) 1999-02-02 US disclosed
US-5703053-A TASTELESS INGESTIBLE COMPOUNDS WHICH REDUCE OR ELIMINATE UNDESIRABLE TASTES IN EATABLES BIORESEARCH, INC. (US) 1997-12-30 US disclosed
US-5700792-A Specific eatable taste modifiers BIORESEARCH, INC. (US) 1997-12-23 US disclosed
US-5665755-A NAPHTHO(1,2-D)IMIDAZOLE-5-SULFONATES (TASTANDS) USED TO REDUCE BITTER OR METALLIC TASTES; FOODS, DRUGS, ARTIFICIAL SWEETENERS; POTASSIUM CHLORIDE BIORESEARCH INC. (US) 1997-09-09 US disclosed
US-5654311-A TASTANDS OF PYRIMIDINE DERIVATIVES, E.G. OROTIC ACID, TO REDUCE OR ELIMINATE A BITTER OR METALLIC TASTE; FOODS; DRUGS; SWEETENERS; POTASSIUM CHLORIDE BIORESEARCH INC. (US) 1997-08-05 US disclosed
US-5650403-A PURINE-BASED COMPOUNDS (TASTANDS, E.G. IOSINE, GUANOSINE AND XANTHINE-5'-PHOSPHATE) USED TO REDUCE OR ELIMINATE A BITTER OR METALLIC TASTE; FOODS; DRUGS; ARTIFICIAL SWEETENERS; POTASSIUM CHLORIDE BIORESEARCH, INC. (US) 1997-07-22 US disclosed
US-5631038-A COMPOUNDS (TASTANDS) TO REDUCE OR ELIMINATE A BITTER OR METALLIC TASTE ARE ADDED TO FOODS CONTAINING SODIUM CHLORIDE BIORESEARCH, INC. (US) 1997-05-20 US disclosed
US-5631294-A PHENOXY- OR PHENYL-ALKANOIC ACIDS BIORESEARCH, INC. (US) 1997-05-20 US disclosed
US-5631295-A 2-(4-METHOXYPHENOXY)PROPIONIC ACID, TAURINE, ASPARTYLPHENYL ALANINE, ASPARTYLTYROSINE AND DIHYDROXYBENZOIC ACID BIORESEARCH, INC. (US) 1997-05-20 US disclosed
US-5631240-A KETONE BIORESEARCH, INC. (US) 1997-05-20 US disclosed
US-5631299-A TAURINE OR AN ACCEPTABLE SALT (A TASTAND) TO REDUCE OR ELIMINATE A BITTER OR METALLIC TASTE; FOODS; DRUGS; SWEETENERS; POTASSIUM CHLORIDE BIORESEARCH, INC. (US) 1997-05-20 US disclosed
US-5631252-A Specific eatable taste modifiers BIORESEARCH, INC. (US) 1997-05-20 US disclosed
US-5631232-A COMPOUNDS (TASTANDS-SUCH AS DERIVATIVES OF ASPARTIC ACID) TO REDUCE OR ELIMINATE A BITTER OR METALLIC TASTE; FOODS; DRUGS; SWEETENERS; POTASSIUM CHLORIDE BIORESEARCH, INC. (US) 1997-05-20 US disclosed
EP-0661932-A4 SPECIFIC EATABLE TASTE MODIFIERS. BIORESEARCH INC (US) 1996-06-05 EP disclosed
EP-0661932-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1995-07-12 EP disclosed
WO-1993010677-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1993-06-10 WO disclosed