SCHEMBL6259101

SCHEMBL6259101

COC(=O)[C@H](N)CC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
KIF11 P52732 1/20 0.36
BHMT Q93088 1/20 0.36
SLC1A1 P43005 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.36
GABRR1 P24046 2/20 0.36
LMNA P02545 1/20 0.36
S1PR1 P21453 1/20 0.36
S1PR3 Q99500 1/20 0.36
GFPT1 Q06210 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL996039 1.00 KMT2A (0.37) KMT2ASMN1; SMN2KIF11BHMTSLC1A1
SCHEMBL416894 1.00 KMT2A (0.37) KMT2ASMN1; SMN2KIF11BHMTSLC1A1
Hydrochloric Acid SCHEMBL4678546 0.98 KMT2A (0.36) KMT2ASMN1; SMN2KIF11BHMTSLC1A1
Ammonia Solution, Strong SCHEMBL7204814 0.98 TDP1 (0.39) KMT2ASMN1; SMN2KIF11BHMTSLC1A1
Hydrochloric Acid SCHEMBL30466615 0.98 KMT2A (0.36) KMT2ASMN1; SMN2KIF11BHMTSLC1A1
Hydrochloric Acid SCHEMBL4678540 0.98 KMT2A (0.36) KMT2ASMN1; SMN2KIF11BHMTSLC1A1
SCHEMBL28364770 0.90 KIF11 (0.33) KMT2ASMN1; SMN2KIF11BHMTSLC1A1
SCHEMBL8894673 0.82 SMN1; SMN2 (0.42) SMN1; SMN2KIF11SLC1A1GFPT1
SCHEMBL29069491 0.81 BHMT (0.35) KMT2ASMN1; SMN2BHMTSLC1A1S1PR1
SCHEMBL16775768 0.81 ALDH1A1 (0.40) KMT2ASMN1; SMN2KIF11SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3636642-B1 INDOLEACETIC ACID DERIVATIVES FOR USE IN THE TREATMENT OF COUGH INST CHINESE MATERIA MEDICA CHINA ACADEMY OF CMS (CN) 2025-12-24 EP disclosed
US-20250257321-A1 METHODS OF TREATING BRAIN INJURY ASTELLAS INSTITUTE FOR REGENERATIVE MEDICINE 2025-08-14 US disclosed
EP-4587443-A1 MACROCYCLIC CFTR MODULATORS Idorsia Pharmaceuticals Ltd (CH) 2025-07-23 EP disclosed
US-12352767-B2 Method of treating cognitive decline associated with neurological diseases based on a decrease in FLT4 expression or activity UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2025-07-08 US disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-12036408-B2 Method and apparatus for multimodal electrical modulation of pain MEDTRONIC SG, LLC (US) 2024-07-16 US disclosed
WO-2024056798-A1 MACROCYCLIC CFTR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2024-03-21 WO disclosed
WO-2024044763-A1 MASS SPECTROMETRY ANALYSIS OF MARKERS FOR ALZHEIMER'S DISEASE EMORY UNIVERSITY (US) 2024-02-29 WO disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
US-11660453-B2 Method and apparatus for multi modal electrical modulation of pain MEDTRONIC SG, LLC (US) 2023-05-30 US disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
CN-111705030-B Escherichia coli genetic engineering bacterium capable of producing L-homoserine with high yield, construction method and strain 浙江工业大学 2023-03-31 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
CN-110418787-B Indole acetic acid derivative and preparation method and medical application thereof 中国中医科学院中药研究所 2022-09-13 CN disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
CN-114206831-A Conjugates of auxin analogs 以色列国家农业部、农村发展农业研究组织·沃尔卡尼中心 2022-03-18 CN disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
EP-1572065-A2 METHOD AND PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF MULTIPLE SCLEROSIS Rappaport Family Institute for Research in the Medical Sciences (IL) 2005-09-14 EP disclosed
WO-2002098346-A2 METHOD AND PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF MULTIPLE SCLEROSIS RAPPAPORT FAMILY INSTITUTE FOR RESEARCH IN THE MEDICAL SCIENCES (IL) 2002-12-12 WO disclosed