SCHEMBL996039

SCHEMBL996039

COC(=O)C(N)CC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
KIF11 P52732 1/20 0.36
BHMT Q93088 1/20 0.36
SLC1A1 P43005 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.36
GABRR1 P24046 2/20 0.36
LMNA P02545 1/20 0.36
S1PR1 P21453 1/20 0.36
S1PR3 Q99500 1/20 0.36
GFPT1 Q06210 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6259101 1.00 KMT2A (0.37) KMT2ASMN1; SMN2KIF11BHMTSLC1A1
SCHEMBL416894 1.00 KMT2A (0.37) KMT2ASMN1; SMN2KIF11BHMTSLC1A1
Hydrochloric Acid SCHEMBL4678546 0.98 KMT2A (0.36) KMT2ASMN1; SMN2KIF11BHMTSLC1A1
Ammonia Solution, Strong SCHEMBL7204814 0.98 TDP1 (0.39) KMT2ASMN1; SMN2KIF11BHMTSLC1A1
Hydrochloric Acid SCHEMBL30466615 0.98 KMT2A (0.36) KMT2ASMN1; SMN2KIF11BHMTSLC1A1
Hydrochloric Acid SCHEMBL4678540 0.98 KMT2A (0.36) KMT2ASMN1; SMN2KIF11BHMTSLC1A1
SCHEMBL28364770 0.90 KIF11 (0.33) KMT2ASMN1; SMN2KIF11BHMTSLC1A1
SCHEMBL8894673 0.82 SMN1; SMN2 (0.42) SMN1; SMN2KIF11SLC1A1GFPT1
SCHEMBL29069491 0.81 BHMT (0.35) KMT2ASMN1; SMN2BHMTSLC1A1S1PR1
SCHEMBL16775768 0.81 ALDH1A1 (0.40) KMT2ASMN1; SMN2KIF11SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119470406-A Phthalic dicarboxaldehyde disinfectant concentration detection test paper and preparation method thereof 山东新华莎罗雅生物技术有限公司 2025-02-18 CN claimed
US-11905527-B2 Gel composition for culturing cells, production method thereof, method for culturing cells, and substrate for culturing cells SHIMADZU CORPORATION (JP) 2024-02-20 US claimed
CN-116829551-A Immunomodulatory antibody drug conjugates 思进公司 2023-09-29 CN claimed
CN-116172984-B Bromopsis oral film-dissolving agent and preparation method thereof 宙晟智维生命科学(上海)有限公司 2023-06-30 CN claimed
CN-116172984-A Bromopsis oral film-dissolving agent and preparation method thereof 宙晟智维生命科学(上海)有限公司 2023-05-30 CN claimed
CN-114907546-A Multifunctional polyurea acid ester derivative and preparation method and application thereof 四川大学 2022-08-16 CN claimed
US-11229621-B2 Pharmaceutical compositions of dimethyl fumarate ARBOR PHARMACEUTICALS, LLC (US) 2022-01-25 US claimed
US-20200155496-A1 Pharmaceutical Compositions of Dimethyl Fumarate HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT 2020-05-21 US claimed
CN-104203297-A Coating composition and medical device TERUMO CORP 2014-12-10 CN claimed
WO-2014160633-A1 PHARMACEUTICAL COMPOSITIONS OF DIMETHYL FUMARATE XENOPORT, INC. (US) 2014-10-02 WO claimed
EP-1586558-A2 Bis-sulfonamide hydroxyethylamino retroviral protease inhinitors G.D. Searle LLC. (US) 2005-10-19 EP claimed
US-20050153876-A1 Compositions of lipopeptide antibiotic derivatives and methods of use thereof MIGENIX INC. (CA) 2005-07-14 US claimed
WO-2005000878-A2 COMPOSITIONS OF LIPOPEPTIDE ANTIBIOTIC DERIVATIVES AND METHODS OF USE THEREOF MIGENIX INC. (CA) 2005-01-06 WO claimed
US-20040063771-A1 Bis-sulfonamide hydroxyethyl-amino retroviral protease inhibitors G.D. SEARLE & CO. (US) 2004-04-01 US claimed
US-6569882-B2 Viricides; enzyme inhibitors G. D. SEARLE & CO. 2003-05-27 US claimed
US-20030013751-A1 Bis-sulfonamide hydroxyethyl-amino retroviral protease inhibitors G.D. SEARLE & CO. (US) 2003-01-16 US claimed
US-6384036-B1 Bis-sulfonamide hydroxyethylamino retroviral protease inhibitors G.D. SEARLE & CO. 2002-05-07 US claimed
US-6143747-A ENZYME INHIBITORS G. D. SEARLE & CO. (US) 2000-11-07 US claimed
EP-0804428-A1 BIS-SULFONAMIDE HYDROXYETHYLAMINO RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1997-11-05 EP claimed
WO-1996022287-A1 BIS-SULFONAMIDE HYDROXYETHYLAMINO RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1996-07-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11229621-B2 Pharmaceutical compositions of dimethyl fumarate FH, SDHB, SDHA KMT2A 1144/4885SMN1; SMN2 2659/4885KIF11 3886/4885
US-20200155496-A1 Pharmaceutical Compositions of Dimethyl Fumarate FH, SDHB, SDHA KMT2A 1144/4885SMN1; SMN2 2659/4885KIF11 3886/4885
US-20030013751-A1 Bis-sulfonamide hydroxyethyl-amino retroviral protease inhibitors DNPEP, PRSS1, PREP KMT2A 873/4885SMN1; SMN2 2504/4885KIF11 4681/4885
US-20050153876-A1 Compositions of lipopeptide antibiotic derivatives and methods of use thereof NRDC, NOD2, NGLY1 KMT2A 4429/4885SMN1; SMN2 4461/4885KIF11 4684/4885
US-20040063771-A1 Bis-sulfonamide hydroxyethyl-amino retroviral protease inhibitors DNPEP, PRSS1, PREP KMT2A 873/4885SMN1; SMN2 2504/4885KIF11 4681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.