SCHEMBL821895

SCHEMBL821895

CC=CC(=O)Oc1ccc(C(=O)O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.55
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
KMT2A Q03164 3/20 0.50
HPGD P15428 1/20 0.46
HTT P42858 1/20 0.46
TP53 P04637 2/20 0.46
TSHR P16473 2/20 0.46
XDH P47989 1/20 0.46
ALDH1A1 P00352 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
PARP15 Q460N3 1/20 0.44
PARP10 Q53GL7 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
MEN1 O00255 1/20 0.43
POLB P06746 1/20 0.43
SRD5A2 P31213 1/20 0.43
PKM P14618 1/20 0.43
ELANE P08246 1/20 0.43
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8622250 1.00 HSD17B10 (0.55) HSD17B10CA1CA2KMT2AHPGD
SCHEMBL7100110 0.87 HSD17B10 (0.50) HSD17B10CA1CA2KMT2AHPGD
SCHEMBL22129150 0.84 ELANE (0.66) KMT2AALDH1A1MEN1POLBSRD5A2
SCHEMBL574099 0.82 KMT2A (0.50) HSD17B10KMT2AHPGDALDH1A1L3MBTL1
SCHEMBL20577757 0.82 HSD17B10 (0.46) HSD17B10CA2KMT2AMEN1POLB
SCHEMBL574100 0.82 KMT2A (0.50) HSD17B10KMT2AHPGDALDH1A1L3MBTL1
SCHEMBL23343677 0.80 HSD17B10 (0.50) HSD17B10CA1CA2KMT2ATP53
SCHEMBL21644509 0.80 HSD17B10 (0.46) HSD17B10KMT2ATP53ALDH1A1L3MBTL1
SCHEMBL21058411 0.80 MEN1 (0.56) CA1CA2KMT2AHPGDALDH1A1
SCHEMBL10694032 0.80 CA2 (0.41) HSD17B10CA2KMT2AHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112074262-B Curable composition for high Wen Guangke-based photopolymerization process and method of preparing crosslinked polymer therefrom 阿莱恩技术有限公司 2024-01-16 CN claimed
EP-3564282-B1 CURABLE COMPOSITION FOR USE IN A HIGH TEMPERATURE PHOTOPOLYMERISATION METHOD ON A LITHOGRAPHY BASIS AND PROCESS FOR THE PREPARATION OF CROSS-LINKED POLYMERS THEREFROM ALIGN TECHNOLOGY INC (US) 2023-06-07 EP claimed
CN-115551907-A Low viscosity light curable resins for direct manufacture of orthodontic appliances 阿莱恩技术有限公司 2022-12-30 CN claimed
EP-4093784-A1 LOW VISCOSITY PHOTO-CURABLE RESINS FOR THE DIRECT FABRICATION OF ORTHODONTIC APPLIANCES Align Technology, Inc. (US) 2022-11-30 EP claimed
EP-3564282-A1 CURABLE COMPOSITION FOR USE IN A HIGH TEMPERATURE PHOTOPOLYMERISATION METHOD ON A LITHOGRAPHY BASIS AND PROCESS FOR THE PREPARATION OF CROSS-LINKED POLYMERS THEREFROM Align Technology, Inc. (US) 2019-11-06 EP claimed
US-20250043047-A1 POLYMERIZABLE MONOMERS AND METHOD OF POLYMERIZING THE SAME ALIGN TECHNOLOGY INC (US) 2025-02-06 US disclosed
US-20240218085-A1 LOW VISCOSITY PHOTO-CURABLE RESINS FOR THE DIRECT FABRICATION OF ORTHODONTIC APPLIANCES ALIGN TECHNOLOGY INC (US) 2024-07-04 US disclosed
US-20240197577-A1 SELF-ADHESIVE DENTAL MATERIAL KULZER GMBH (DE) 2024-06-20 US disclosed
US-20240148613-A1 DENTAL POLYMERIZATION KIT SUN MEDICAL CO., LTD. (JP) 2024-05-09 US disclosed
CN-117736392-A Curable composition for high Wen Guangke-based photopolymerization process and method of preparing crosslinked polymer therefrom 阿莱恩技术有限公司 2024-03-22 CN disclosed
EP-4316453-A1 DENTAL POLYMERIZATION KIT Sun Medical Co., Ltd. (JP) 2024-02-07 EP disclosed
CN-112074262-B Curable composition for high Wen Guangke-based photopolymerization process and method of preparing crosslinked polymer therefrom 阿莱恩技术有限公司 2024-01-16 CN disclosed
US-10781275-B2 Polymerizable monomers and method of polymerizing the same ALIGN TECHNOLOGY, INC. (US) 2020-09-22 US disclosed
US-20200268483-A1 MICRO APPLICATOR FOR USE WITH DENTAL ADHESIVES KULZER GMBH (DE) 2020-08-27 US disclosed
US-20200040113-A1 POLYMERIZABLE MONOMERS AND METHOD OF POLYMERIZING THE SAME ALIGN TECHNOLOGY, INC. 2020-02-06 US disclosed
US-20190345276-A1 POLYMERIZABLE MONOMERS AND METHOD OF POLYMERIZING THE SAME TU WIEN (AT) 2019-11-14 US disclosed
US-8664335-B2 Thermally crosslinked polymeric compositions and methods of making the same GEORGIA TECH RESEARCH CORPORATION (US) 2014-03-04 US disclosed
US-20110269915-A1 THERMALLY CROSSLINKED POLYMERIC COMPOSITIONS AND METHODS OF MAKING THE SAME GEORGIA TECH RESEARCH CORPORATION (US) 2011-11-03 US disclosed
WO-2010005734-A1 THERMALLY CROSSLINKED POLYMERIC COMPOSITIONS AND METHODS OF MAKING THE SAME GEORGIA TECH RESEARCH CORPORATION (US) 2010-01-14 WO disclosed
US-5484551-A Substituted phenyl 4-[(E)-alk-2-enoyloxy]benzoates HOFFMANN-LA ROCHE INC. (US) 1996-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240197577-A1 SELF-ADHESIVE DENTAL MATERIAL CAD, MTHFD2, MAT2B HSD17B10 2017/4885CA1 561/4885CA2 2881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.