Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | GRM8 | O00222 | 2/20 | 0.53 |
| ▸ | GRM6 | O15303 | 2/20 | 0.53 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.53 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.53 |
| ▸ | GSR | P00390 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.53 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.53 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156358 | 0.87 | KMT2A (0.45) | ALOX15BLMPMP22KMT2ANOD1 | |
| SCHEMBL1226472 | 0.87 | KMT2A (0.45) | ALOX15BLMPMP22KMT2ANOD1 | |
| SCHEMBL22042 | 0.87 | KMT2A (0.45) | ALOX15BLMPMP22KMT2ANOD1 | |
| SCHEMBL4655464 | 0.84 | FOLH1 (0.55) | GRM8GRM6GRM7GRM4GRIN2D | |
| SCHEMBL2450582 | 0.84 | FOLH1 (0.55) | GRM8GRM6GRM7GRM4GRIN2D | |
| Glutamine SCHEMBL8427117 | 0.82 | NOD1 (0.65) | ALOX15BLMPMP22KMT2AGRM8 | |
| Glutamine SCHEMBL29032116 | 0.82 | NOD1 (0.65) | ALOX15BLMPMP22KMT2AGRM8 | |
| Glutamine SCHEMBL27968519 | 0.81 | ALOX15 (0.54) | ALOX15BLMPMP22KMT2AGRM8 | |
| SCHEMBL2619413 | 0.81 | GRM8 (0.59) | ALOX15BLMPMP22KMT2AGRM8 | |
| Glutamine SCHEMBL9165715 | 0.80 | PMP22 (0.86) | ALOX15BLMPMP22KMT2AGRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0989864-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING ANTIBODY-ENZYME CONJUGATES IN COMBINATION WITH PRODRUGS | THE SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2000-04-05 | — | — | EP | disclosed |
| WO-1998056425-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING ANTIBODY-ENZYME CONJUGATES IN COMBINATION WITH PRODRUGS | THE SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 1998-12-17 | — | — | WO | disclosed |