Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3343610 | 0.83 | CYP1A2 (0.43) | MAPTSMN1; SMN2THRBALDH1A1KDM4E | |
| SCHEMBL8216214 | 0.82 | KDM4E (0.39) | MAPTSMN1; SMN2THRBKDM4ECYP1A2 | |
| SCHEMBL3344136 | 0.79 | BAZ2B (0.46) | MAPTSMN1; SMN2ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL3343855 | 0.72 | MAPT (0.44) | MAPTSMN1; SMN2ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL8217024 | 0.71 | RAB9A (0.41) | SMN1; SMN2LMNA | |
| SCHEMBL8221375 | 0.71 | KMO (0.43) | MAPTSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL3341192 | 0.71 | ALDH1A1 (0.54) | MAPTSMN1; SMN2ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL3340085 | 0.71 | KMO (0.40) | SMN1; SMN2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL3341133 | 0.71 | JAK2 (0.53) | MAPTSMN1; SMN2ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL544894 | 0.68 | MAPT (0.62) | MAPTSMN1; SMN2THRBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031500-A1 | 4-PHENOXY-NICOTINE ACID DERIVATIVES AND USE THEREOF AS PPAR-MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-20 | — | — | WO | disclosed |