Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.58 |
| ▸ | BTK | Q06187 | 1/20 | 0.58 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CCKBR | P32239 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2301376 | 0.87 | PPARA (0.54) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL19020373 | 0.87 | PPARA (0.54) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL17446701 | 0.87 | PPARA (0.54) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL24945915 | 0.86 | CCKBR (0.49) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL3817109 | 0.86 | PPARA (0.55) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL1517760 | 0.86 | PPARA (0.55) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL13007476 | 0.86 | PPARA (0.55) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL376018 | 0.86 | PPARA (0.61) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL2011835 | 0.86 | PPARA (0.55) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL428113 | 0.86 | PPARA (0.61) | PPARAKLK7KLK5CTSSPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511039-B2 | β-sheet mimetics and use thereof as inhibitors of biologically active peptides or proteins | MYRIAD GENETICS, INC. (US) | 2009-03-31 | — | — | US | disclosed |
| US-20060276408-A1 | Beta-sheet mimetics and use thereof as inhibitors of biologically active peptides or proteins | MYRIAD GENETICS, INCORPORATED (US) | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276408-A1 | Beta-sheet mimetics and use thereof as inhibitors of biologically active peptides or proteins | SERPINB1, SERPINE1, SERPINA2 | JAK3 4498/4885BTK 2013/4885PPARA 3893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.