Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | P2RY10 | O00398 | 3/20 | 0.39 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5707863 | 0.98 | DGKA (0.52) | ALDH1A1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL12375161 | 0.94 | DGKA (0.57) | ALDH1A1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL15025025 | 0.93 | DGKA (0.55) | ALDH1A1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL25967079 | 0.91 | ALDH1A1 (0.53) | ALDH1A1DGKADNM1ACHEGAA | |
| SCHEMBL821433 | 0.89 | DGKA (0.52) | ALDH1A1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL10001061 | 0.89 | DGKA (0.59) | ALDH1A1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL10918414 | 0.88 | DGKA (0.56) | ALDH1A1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL13343463 | 0.88 | ALDH1A1 (0.58) | ALDH1A1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL2299235 | 0.88 | DGKA (0.56) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL6651939 | 0.88 | DGKA (0.56) | DGKAPRSS1PRSS2PRSS3DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110287102-A1 | CHAIN EXTENDERS | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287102-A1 | CHAIN EXTENDERS | UMPS, PUF60, SMCHD1 | ALDH1A1 333/4885DGKA 1315/4885PRSS1 649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.