Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | WNT3 | P56703 | 2/20 | 0.43 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.43 |
| ▸ | UCHL1 | P09936 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8219832 | 0.88 | WNT3 (0.44) | NPC1HRH2HRH1MEN1KMT2A | |
| SCHEMBL4775951 | 0.87 | TDP1 (0.41) | HSD11B1ALDH1A1DRD2DRD1DRD4 | |
| SCHEMBL1251121 | 0.83 | NPC1 (0.53) | NPC1HRH2HRH1MEN1KMT2A | |
| SCHEMBL2136252 | 0.83 | NPC1 (0.53) | NPC1HRH2HRH1MEN1KMT2A | |
| SCHEMBL1795426 | 0.83 | NPC1 (0.53) | NPC1HRH2HRH1MEN1KMT2A | |
| SCHEMBL25353468 | 0.82 | LMNA (0.56) | NPC1HRH2HRH1MEN1KMT2A | |
| SCHEMBL8221674 | 0.82 | NPC1 (0.55) | NPC1HRH2HRH1MEN1KMT2A | |
| SCHEMBL2134992 | 0.81 | NPC1 (0.54) | NPC1HRH2HRH1MEN1KMT2A | |
| SCHEMBL24443452 | 0.81 | NPC1 (0.57) | NPC1HRH2HRH1MEN1KMT2A | |
| SCHEMBL2136506 | 0.81 | NPC1 (0.54) | NPC1HRH2HRH1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |