Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8220085 | 0.87 | NPC1 (0.47) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL4725359 | 0.86 | DRD2 (0.42) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL4779559 | 0.77 | HPGD (0.44) | TDP1L3MBTL1ALDH1A1HSD11B1CA2 | |
| SCHEMBL5172182 | 0.77 | MCL1 (0.46) | ALDH1A1 | |
| SCHEMBL3088285 | 0.77 | MCL1 (0.46) | ALDH1A1 | |
| SCHEMBL20524450 | 0.77 | POLB (0.51) | L3MBTL1ALDH1A1HSD11B1HTT | |
| SCHEMBL4779200 | 0.76 | CXCR2 (0.41) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL5733006 | 0.76 | NPC1 (0.51) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL8219832 | 0.74 | WNT3 (0.44) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL440331 | 0.73 | KDM4E (0.45) | TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |