SCHEMBL8220099

SCHEMBL8220099

CC(C)(C)[Si](C)(C)C1=C([Si](NC2CCCCC2)(c2ccccc2)c2ccccc2)CC=C1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8216349 0.89 EPHX2 (0.33) LMNA
SCHEMBL8218119 0.81
SCHEMBL8214917 0.80
SCHEMBL8215481 0.80
SCHEMBL8217606 0.79 LMNA (0.34) LMNA
SCHEMBL8215527 0.79
SCHEMBL8208147 0.77 GAA (0.36) LMNA
SCHEMBL8216556 0.73 KDM4E (0.34) LMNA
SCHEMBL8215565 0.72 CNR2 (0.37)
SCHEMBL8207170 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6136995-A Process for producing aminosilane compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-24 US disclosed