SCHEMBL8215565

SCHEMBL8215565

CCCCCC1=C([Si](NC2CCCCC2)(c2ccccc2)c2ccccc2)CC=C1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 10/20 0.37
CNR1 P21554 6/20 0.37
EPHX1 P07099 3/20 0.34
EPHX2 P34913 1/20 0.34
FAAH O00519 2/20 0.32
ICMT O60725 1/20 0.32
ALB P02768 1/20 0.32
FLT3 P36888 1/20 0.31
TYRO3 Q06418 1/20 0.31
MERTK Q12866 1/20 0.31
GAS6 Q14393 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8214706 0.87 CNR2 (0.36) CNR2CNR1EPHX1EPHX2FAAH
SCHEMBL8215609 0.87 CNR2 (0.36) CNR2CNR1EPHX1EPHX2FAAH
SCHEMBL8220095 0.80 GPR84 (0.33)
SCHEMBL8208020 0.80 KCNH3 (0.35) EPHX1
SCHEMBL8215591 0.80 EPHX1 (0.37) CNR2CNR1EPHX1EPHX2
SCHEMBL8216356 0.79 DHFR (0.32) FAAH
SCHEMBL8216453 0.79 DHFR (0.32) FAAH
SCHEMBL8207977 0.79 KCNH3 (0.35) EPHX1
SCHEMBL8218873 0.79 KCNH3 (0.35) EPHX1
SCHEMBL8215717 0.79 SIGMAR1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6136995-A Process for producing aminosilane compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-24 US disclosed