Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.44 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
| ▸ | Q9HBH1 | 1/20 | 0.36 | |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | FPR3 | P25089 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11930156 | 1.00 | CTSV (0.44) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL8225467 | 0.91 | CTSV (0.45) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL8227722 | 0.89 | CTSK (0.42) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL11930157 | 0.89 | CTSK (0.42) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL11936782 | 0.89 | CTSK (0.41) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL8219312 | 0.89 | CTSK (0.41) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL13559977 | 0.89 | CTSV (0.43) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL11938018 | 0.89 | CTSV (0.43) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL8228348 | 0.87 | CTSB (0.40) | CTSVCTSLCTSBELANECMA1 | |
| SCHEMBL11936553 | 0.87 | CTSB (0.40) | CTSVCTSLCTSBELANECMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2518079-A2 | HCV/HIV inhibitors and their uses | Novartis AG (CH) | 2012-10-31 | — | — | EP | disclosed |
| WO-2007133865-A2 | HCV/HIV INHIBITORS AN THEIR USES | NOVARTIS AG (CH) | 2007-11-22 | — | — | WO | disclosed |