Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438693 | 0.93 | ALDH1A1 (0.49) | ALDH1A1TSHRHTTMAPTCES1 | |
| SCHEMBL9164231 | 0.85 | SMN1; SMN2 (0.44) | ALDH1A1TSHRHTTKMT2AMEN1 | |
| SCHEMBL9164480 | 0.84 | LMNA (0.51) | ALDH1A1HTTLMNACYP3A4TDP1 | |
| SCHEMBL28888069 | 0.83 | SRC (0.51) | ALDH1A1TSHRHTTMAPTCES1 | |
| SCHEMBL10956205 | 0.82 | ALDH1A1 (0.49) | ALDH1A1TSHRHTTMAPTCES1 | |
| SCHEMBL11086781 | 0.81 | MAPT (0.50) | ALDH1A1TSHRHTTMAPTCES1 | |
| SCHEMBL4808857 | 0.78 | CES1 (0.47) | ALDH1A1TSHRMAPTCES1SRC | |
| SCHEMBL8898434 | 0.77 | TSHR (0.44) | ALDH1A1TSHRHTTMAPTCES1 | |
| SCHEMBL528085 | 0.77 | TSHR (0.42) | ALDH1A1TSHRHTTMAPTKMT2A | |
| SCHEMBL3305369 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRHTTMAPTCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082588-A | Hygrometers | ELLIOTT STANLEY B (US) | 1992-01-21 | — | — | US | claimed |
| US-9580571-B2 | Aromatic acylation with cyclic anhydride for plasticizer production | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2017-02-28 | — | — | US | disclosed |
| US-9512296-B2 | Aromatic acylation with cyclic anhydride for plasticizer production | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2016-12-06 | — | — | US | disclosed |
| US-20140100384-A1 | AROMATIC ACYLATION WITH CYCLIC ANHYDRIDE FOR PLASTICIZER PRODUCTION | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2014-04-10 | — | — | US | disclosed |
| US-20140100383-A1 | AROMATIC ACYLATION WITH CYCLIC ANHYDRIDE FOR PLASTICIZER PRODUCTION | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2014-04-10 | — | — | US | disclosed |
| US-8604114-B2 | Aromatic acylation with cyclic anhydride for plasticizer production | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2013-12-10 | — | — | US | disclosed |
| US-20110160371-A1 | AROMATIC ACYLATION WITH CYCLIC ANHYDRIDE FOR PLASTICIZER PRODUCTION | EXXONMOBILE RESEARCH AND ENGINEERING COMPANY (US) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160371-A1 | AROMATIC ACYLATION WITH CYCLIC ANHYDRIDE FOR PLASTICIZER PRODUCTION | ACAD11, ACOT7, ACOX3 | ALDH1A1 312/4885TSHR 3934/4885HTT 1384/4885 |
| US-20140100383-A1 | AROMATIC ACYLATION WITH CYCLIC ANHYDRIDE FOR PLASTICIZER PRODUCTION | ACAD11, ACOT7, ACOX3 | ALDH1A1 312/4885TSHR 3934/4885HTT 1384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.