Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8184546 | 0.92 | NPC1 (0.45) | KMT2AMEN1CYP2D6ALDH1A1LMNA | |
| SCHEMBL8185953 | 0.76 | CYP2A6 (0.44) | ALDH1A1RAB9ANPC1GSK3BEPHX2 | |
| SCHEMBL10519134 | 0.75 | ATM (0.41) | KMT2AMEN1LMNACES2CES1 | |
| SCHEMBL8171346 | 0.75 | MAPT (0.50) | KMT2AMEN1ALDH1A1LMNARAB9A | |
| SCHEMBL3587635 | 0.74 | POLB (0.41) | KMT2AMEN1CYP2D6ALDH1A1LMNA | |
| SCHEMBL8230111 | 0.72 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL728685 | 0.71 | KMT2A (0.72) | KMT2AMEN1CYP2D6ALDH1A1LMNA | |
| SCHEMBL8326384 | 0.71 | GBA1 (0.42) | KMT2AMEN1CYP2D6LMNAATM | |
| SCHEMBL8993926 | 0.69 | ESR1 (0.64) | KMT2AMEN1CYP2D6ALDH1A1LMNA | |
| SCHEMBL28428293 | 0.69 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1LMNACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968178-A1 | N-SULPHONYL AND N-SULPHINYL AMINO ACID AMIDES AS MICROBICIDES | Novartis AG (CH) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998038160-A1 | N-SULPHONYL AND N-SULPHINYL AMINO ACID AMIDES AS MICROBICIDES | NOVARTIS AG (CH) | 1998-09-03 | — | — | WO | disclosed |