Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 7/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374452 | 0.83 | ACHE (0.55) | GAAALDH1A1ACHEMGAMSI | |
| SCHEMBL731156 | 0.81 | ABCC4 (0.46) | ALDH1A1LMNAACHEHRH4HRH3 | |
| SCHEMBL28289954 | 0.81 | ACHE (0.49) | ALDH1A1LMNAACHEHRH4HRH3 | |
| SCHEMBL434612 | 0.81 | CA12 (0.43) | GAAALDH1A1LMNA | |
| SCHEMBL13032956 | 0.81 | THRB (0.47) | GAAALDH1A1ACHEMGAMSI | |
| SCHEMBL433341 | 0.80 | EGLN1 (0.50) | GAAALDH1A1LMNAACHE | |
| SCHEMBL11339356 | 0.80 | ACHE (0.51) | ALDH1A1LMNAACHEEPHX2 | |
| SCHEMBL22588787 | 0.79 | ACHE (0.59) | ACHEHRH4HRH3EPHX2 | |
| SCHEMBL2482646 | 0.78 | GAA (0.59) | GAAALDH1A1MGAMSIMGAM2 | |
| SCHEMBL16329686 | 0.78 | TSHR (0.46) | GAAALDH1A1MGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057208-A2 | HCV NS3 PROTEASE INHIBITORS | MERCK & CO., INC. (US) | 2008-05-15 | — | — | WO | disclosed |