SCHEMBL822022

SCHEMBL822022

CNc1nc(NC(=O)c2cccc(C)c2)nc(Nc2ccccc2)n1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 10/20 0.59
KCNK9 Q9NPC2 10/20 0.59
MEN1 O00255 4/20 0.59
KMT2A Q03164 4/20 0.59
POLB P06746 1/20 0.59
KCNH2 Q12809 1/20 0.56
RHOA P61586 1/20 0.53
RXFP1 Q9HBX9 1/20 0.52
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
NT5E P21589 1/20 0.51
GRM5 P41594 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
TP53 P04637 1/20 0.49
LMNA P02545 1/20 0.49
GAA P10253 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10083715 0.90 KCNK3 (0.59) KCNK3KCNK9MEN1KMT2APOLB
SCHEMBL2623156 0.89 GRM5 (0.60) KCNK3KCNK9MEN1KMT2APOLB
SCHEMBL821849 0.88 LMNA (0.58) KCNK3KCNK9MEN1KMT2ARHOA
SCHEMBL10083493 0.88 RHOA (0.53) KCNK3KCNK9MEN1KMT2APOLB
SCHEMBL821854 0.87 KCNK3 (0.55) KCNK3KCNK9MEN1KMT2APOLB
SCHEMBL822369 0.86 MAPT (0.54) MEN1KMT2ARHOARXFP1NPC1
SCHEMBL2623120 0.85 KCNK3 (0.56) KCNK3KCNK9MEN1KMT2APOLB
SCHEMBL821852 0.84 NPC1 (0.64) KCNK3KCNK9MEN1KMT2APOLB
SCHEMBL4285475 0.84 KMT2A (0.67) KCNK3KCNK9MEN1KMT2APOLB
SCHEMBL822019 0.83 GRM5 (0.53) KCNK3KCNK9MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9151883-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-10-06 US disclosed
US-9151883-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-10-06 US disclosed
US-8937696-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-01-20 US disclosed
US-8937696-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-01-20 US disclosed
US-8906475-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2014-12-09 US disclosed
US-8906475-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2014-12-09 US disclosed
US-20140318413-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2014-10-30 US disclosed
US-20140318413-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2014-10-30 US disclosed
US-8792071-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2014-07-29 US disclosed
US-8792071-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2014-07-29 US disclosed
US-20120204757-A1 Cellulose Acylate Film, Retardation Film, Polarizer and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2012-08-16 US disclosed
US-20120180697-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-07-19 US disclosed
US-20120180697-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-07-19 US disclosed
US-20120177848-A1 CELLULOSE ACYLATE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-07-12 US disclosed
US-20120177848-A1 CELLULOSE ACYLATE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-07-12 US disclosed
US-20120018685-A1 Optical film, retardation film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
US-20120018685-A1 Optical film, retardation film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
US-20110255037-A1 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-10-20 US disclosed
US-20110076423-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110076423-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed