SCHEMBL822369

SCHEMBL822369

CNc1nc(NC(=O)c2ccc(C)cc2)nc(Nc2ccccc2)n1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.54
LMNA P02545 1/20 0.52
GAA P10253 1/20 0.52
ADORA2A P29274 2/20 0.52
ADORA1 P30542 2/20 0.52
TNIK Q9UKE5 1/20 0.52
HTT P42858 1/20 0.52
NPC1 O15118 4/20 0.51
RAB9A P51151 4/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
NAMPT P43490 2/20 0.51
ADORA3 P0DMS8 2/20 0.51
KCNH3 Q9ULD8 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.47
RHOA P61586 1/20 0.47
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
NTSR1 P30989 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL821849 0.92 LMNA (0.58) LMNAGAAADORA1HTTNAMPT
SCHEMBL10083491 0.89 ADORA2A (0.55) MAPTADORA2AADORA1TNIKNPC1
SCHEMBL10083489 0.89 AURKA (0.53) LMNAGAAHTTNPC1RAB9A
SCHEMBL821480 0.86 MAPT (0.54) MAPTADORA2AADORA1TNIKHTT
SCHEMBL822022 0.86 KCNK3 (0.59) LMNAGAANPC1RAB9ASMN1; SMN2
SCHEMBL822370 0.86 KMT2A (0.56) MAPTGAAADORA2AADORA1HTT
SCHEMBL2623122 0.83 ADORA1 (0.49) MAPTADORA2AADORA1TNIKNPC1
SCHEMBL10083493 0.81 RHOA (0.53) MAPTLMNAGAAADORA1HTT
SCHEMBL10073738 0.80 RAB9A (0.49) MAPTGAAADORA2AADORA1NPC1
SCHEMBL27966498 0.80 MEN1 (0.53) MAPTLMNAGAAADORA1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9151883-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-10-06 US disclosed
US-9151883-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-10-06 US disclosed
US-8937696-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-01-20 US disclosed
US-8937696-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-01-20 US disclosed
US-8906475-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2014-12-09 US disclosed
US-8906475-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2014-12-09 US disclosed
US-20140318413-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2014-10-30 US disclosed
US-20140318413-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2014-10-30 US disclosed
US-8792071-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2014-07-29 US disclosed
US-8792071-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2014-07-29 US disclosed
US-20120204757-A1 Cellulose Acylate Film, Retardation Film, Polarizer and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2012-08-16 US disclosed
US-20120180697-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-07-19 US disclosed
US-20120180697-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-07-19 US disclosed
US-20120177848-A1 CELLULOSE ACYLATE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-07-12 US disclosed
US-20120177848-A1 CELLULOSE ACYLATE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-07-12 US disclosed
US-20120018685-A1 Optical film, retardation film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
US-20120018685-A1 Optical film, retardation film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
US-20110255037-A1 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-10-20 US disclosed
US-20110076423-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110076423-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed