Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689735 | 0.83 | VCAM1 (0.66) | VCAM1HTTTDP1ALDH1A1LMNA | |
| Nitrogen SCHEMBL28796067 | 0.81 | VCAM1 (0.64) | VCAM1HTTTDP1ALDH1A1LMNA | |
| SCHEMBL7821980 | 0.80 | ALDH1A1 (0.52) | HTTTDP1ALDH1A1LMNACYP3A4 | |
| SCHEMBL1706658 | 0.72 | VCAM1 (0.59) | VCAM1HTTTDP1ALDH1A1LMNA | |
| SCHEMBL6865120 | 0.71 | ALDH1A1 (0.60) | VCAM1HTTTDP1ALDH1A1LMNA | |
| SCHEMBL73860 | 0.69 | VCAM1 (0.70) | VCAM1TDP1ALDH1A1LMNAXDH | |
| SCHEMBL1343971 | 0.69 | VCAM1 (0.64) | VCAM1TDP1ALDH1A1LMNAXDH | |
| SCHEMBL29557322 | 0.69 | VCAM1 (0.64) | VCAM1TDP1ALDH1A1LMNAXDH | |
| SCHEMBL28857833 | 0.68 | TDP1 (0.57) | VCAM1HTTTDP1ALDH1A1LMNA | |
| Fluoride SCHEMBL28259583 | 0.68 | VCAM1 (0.68) | VCAM1TDP1ALDH1A1LMNAXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019720-A1 | COMBINATORIAL PROCESS FOR PREPARING TETRAHYDROQUINOLINE LIBRARIES | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998027427-A1 | COMBINATORIAL PROCESS FOR PREPARING TETRAHYDROQUINOLINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |