Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29557322 | 1.00 | VCAM1 (0.64) | VCAM1ALDH1A1TSHRTDP1LMNA | |
| SCHEMBL1232789 | 0.85 | ALDH1A1 (0.60) | VCAM1ALDH1A1TSHRTDP1LMNA | |
| SCHEMBL27638357 | 0.83 | ALDH1A1 (0.62) | VCAM1ALDH1A1TSHRTDP1LMNA | |
| SCHEMBL73860 | 0.82 | VCAM1 (0.70) | VCAM1ALDH1A1TSHRTDP1LMNA | |
| SCHEMBL23648373 | 0.81 | ALDH1A1 (0.60) | VCAM1ALDH1A1TSHRTDP1LMNA | |
| SCHEMBL16957776 | 0.81 | ALDH1A1 (0.60) | VCAM1ALDH1A1TSHRTDP1LMNA | |
| SCHEMBL29980060 | 0.81 | ALDH1A1 (0.60) | VCAM1ALDH1A1TSHRTDP1LMNA | |
| Fluoride SCHEMBL28259583 | 0.81 | VCAM1 (0.68) | VCAM1ALDH1A1TSHRTDP1LMNA | |
| SCHEMBL24401755 | 0.80 | ALDH1A1 (0.58) | VCAM1ALDH1A1TSHRTDP1LMNA | |
| SCHEMBL698847 | 0.79 | VCAM1 (0.66) | VCAM1ALDH1A1TSHRTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429274-B2 | Agent and method for the oxidative coloring of keratin fibers | WELLA AG (DE) | 2008-09-30 | — | — | US | claimed |
| US-20070079452-A1 | Agent and method for the oxidative coloring of keratin fibers | Wella GmbH (DE) | 2007-04-12 | — | — | US | claimed |
| EP-1699426-A1 | AGENT AND METHOD FOR OXIDATIVELY DYEING KERATIN FIBERS | Wella Aktiengesellschaft (DE) | 2006-09-13 | — | — | EP | claimed |
| WO-2005060927-A1 | AGENT AND METHOD FOR OXIDATIVELY DYEING KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2005-07-07 | — | — | WO | claimed |
| EP-4663636-A2 | TRIFLUOROMETHYL SUBSTITUTED PYRAZOLES AS HUMAN PLASMA KALLIKREIN INHIBITORS | BioCryst Pharmaceuticals, Inc. (US) | 2025-12-17 | — | — | EP | disclosed |
| US-20250270171-A1 | HUMAN PLASMA KALLIKREIN INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2025-08-28 | — | — | US | disclosed |
| US-20250257040-A1 | HUMAN PLASMA KALLIKREIN INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2025-08-14 | — | — | US | disclosed |
| US-20250214963-A1 | SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH | PFIZER INC. | 2025-07-03 | — | — | US | disclosed |
| EP-4180424-B1 | SUBSTITUTED PYRAZOLES AS HUMAN PLASMA KALLIKREIN INHIBITORS | BIOCRYST PHARM INC (US) | 2025-06-25 | — | — | EP | disclosed |
| US-12162838-B2 | Human plasma kallikrein inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2024-12-10 | — | — | US | disclosed |
| US-12116346-B2 | Human plasma kallikrein inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2024-10-15 | — | — | US | disclosed |
| CN-113307772-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2024-06-28 | — | — | CN | disclosed |
| EP-0128382-B1 | 1-ALKYL-2-ISOCYANATOMETHYL-ISOCYANATO-CYCLOHEXANES AND/OR 1-ALKYL-4-ISOCYANATO-METHYL-ISOCYANATO-CYCLOHEXANES AND THE LIKE DIAMINES, PROCESSES FOR THEIR PREPARATION, AND USE | BASF Aktiengesellschaft (DE) | 1989-09-27 | — | — | EP | disclosed |
| EP-0091054-B1 | 1-ALKYL-2-ISOCYANATOMETHYL-ISOCYANATO PHENYL AND/OR 1-ALKYL-4-ISOCYANATOMETHYL-ISOCYANATO PHENYL, METHOD FOR THEIR PREPARATION AND USE | BASF Aktiengesellschaft (DE) | 1985-10-02 | — | — | EP | disclosed |
| US-4512929-A | POLYURETHANE MONOMERS, PLANT SAFENING AGENT | BASF AKTIENGESELLSCHAFT (DE) | 1985-04-23 | — | — | US | disclosed |
| EP-0128382-A1 | 1-Alkyl-2-isocyanatomethyl-isocyanato-cyclohexanes and/or 1-alkyl-4-isocyanato-methyl-isocyanato-cyclohexanes and the like diamines, processes for their preparation, and use | BASF Aktiengesellschaft (DE) | 1984-12-19 | — | — | EP | disclosed |
| EP-0091054-A1 | 1-Alkyl-2-isocyanatomethyl-isocyanato phenyl and/or 1-alkyl-4-isocyanatomethyl-isocyanato phenyl, method for their preparation and use | BASF Aktiengesellschaft (DE) | 1983-10-12 | — | — | EP | disclosed |
| US-4167629-A | OPTICAL BRIGHTENERS | SANDOZ LTD. (CH) | 1979-09-11 | — | — | US | disclosed |
| US-4088497-A | Acutance agents for use in thermally-developable photosensitive compositions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1978-05-09 | — | — | US | disclosed |
| US-4033948-A | METHINE ARYLIDENE DYES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250214963-A1 | SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH | GPR119, INSR, LYAR | VCAM1 3893/4885ALDH1A1 1427/4885TSHR 282/4885 |
| US-12116346-B2 | Human plasma kallikrein inhibitors | KLKB1, KLK5, KLK1 | VCAM1 574/4885ALDH1A1 1136/4885TSHR 3844/4885 |
| US-20250270171-A1 | HUMAN PLASMA KALLIKREIN INHIBITORS | KLKB1, KLK5, KLK1 | VCAM1 574/4885ALDH1A1 1136/4885TSHR 3844/4885 |
| US-20250257040-A1 | HUMAN PLASMA KALLIKREIN INHIBITORS | KLKB1, KLK5, KLK1 | VCAM1 574/4885ALDH1A1 1136/4885TSHR 3844/4885 |
| US-20070079452-A1 | Agent and method for the oxidative coloring of keratin fibers | KRT18, KIT, CKMT1A; CKMT1B | VCAM1 2827/4885ALDH1A1 129/4885TSHR 4782/4885 |
| US-12162838-B2 | Human plasma kallikrein inhibitors | KLKB1, KLK5, KLK1 | VCAM1 574/4885ALDH1A1 1136/4885TSHR 3844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.