Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | DAGLA | Q9Y4D2 | 4/20 | 0.44 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.44 |
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | PDE8B | O95263 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828162 | 0.87 | GPR119 (0.48) | NR1H2NR1H3KDM1ADAGLAHCRTR1 | |
| SCHEMBL14939652 | 0.87 | NR1H2 (0.46) | NR1H2NR1H3KDM1ADAGLAHCRTR1 | |
| SCHEMBL14939654 | 0.87 | NR1H2 (0.46) | NR1H2NR1H3KDM1ADAGLAHCRTR1 | |
| SCHEMBL10132498 | 0.84 | NR1H2 (0.48) | NR1H2NR1H3KDM1ADAGLAUCHL1 | |
| SCHEMBL14940097 | 0.83 | NR1H2 (0.47) | USP30NR1H2NR1H3KDM1ADAGLA | |
| SCHEMBL10132370 | 0.83 | ALDH1A1 (0.50) | USP30NR1H2NR1H3UCHL1HCRTR1 | |
| SCHEMBL10132273 | 0.83 | GPR119 (0.49) | NR1H2NR1H3DAGLAUCHL1HCRTR1 | |
| SCHEMBL14940096 | 0.83 | NR1H2 (0.47) | USP30NR1H2NR1H3KDM1ADAGLA | |
| SCHEMBL17056240 | 0.83 | USP30 (0.49) | USP30NR1H2NR1H3KDM1AUCHL1 | |
| SCHEMBL1992473 | 0.82 | FPR3 (0.52) | USP30NR1H2NR1H3KDM1AUCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |