Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | GLB1 | P16278 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 4/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8214143 | 0.82 | ALDH1A1 (0.54) | MAPTTP53MAPK13GCGRMAPK12 | |
| SCHEMBL3270763 | 0.81 | BRAF (0.50) | ALOX15MAPTMAPK13GCGRMAPK12 | |
| SCHEMBL14298815 | 0.78 | MEN1 (0.45) | MAPTKMT2AMEN1NPSR1NPC1 | |
| SCHEMBL14711720 | 0.75 | NR1H2 (0.41) | MAPTKMT2AMEN1NPSR1NPC1 | |
| SCHEMBL14790653 | 0.74 | LMNA (0.36) | MAPTKMT2AMEN1NPSR1NPC1 | |
| SCHEMBL49947 | 0.73 | ALOX15 (0.81) | ALOX15MAPTKMT2AMEN1GLB1 | |
| SCHEMBL5533450 | 0.73 | ALOX15 (0.81) | ALOX15MAPTKMT2AMEN1GLB1 | |
| SCHEMBL8214582 | 0.73 | KMT2A (0.40) | ALOX15MAPTTP53KMT2AMEN1 | |
| SCHEMBL15885797 | 0.72 | BRAF (0.46) | MAPK13MAPK12MAPK11MAPK14ESR1 | |
| SCHEMBL8213534 | 0.72 | ESR1 (0.40) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021871-A2 | TRIAZOLYL ACYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |