Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.52 |
| ▸ | PDK1 | Q15118 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8219821 | 0.86 | THRB (0.60) | THRBHDAC6HDAC1TP53 | |
| SCHEMBL8226183 | 0.85 | THRB (0.66) | THRBPDK1HDAC6HDAC1NPC1 | |
| SCHEMBL8225281 | 0.85 | THRB (0.56) | THRBPDK1HDAC6HDAC1NPC1 | |
| SCHEMBL8229490 | 0.84 | THRB (0.55) | THRBPDK1HDAC6HDAC1NPC1 | |
| SCHEMBL8228581 | 0.83 | THRB (0.59) | THRBHDAC6HDAC1NPC1MAPT | |
| SCHEMBL8229448 | 0.83 | THRB (0.59) | THRBPDK1HDAC6HDAC1NPC1 | |
| SCHEMBL8231039 | 0.80 | THRB (0.56) | THRBGAATSHRKMT2A | |
| SCHEMBL5364592 | 0.80 | THRB (0.57) | THRBGAAHDAC6HDAC1MEN1 | |
| SCHEMBL8228557 | 0.77 | THRB (0.58) | THRBHDAC6HDAC1 | |
| SCHEMBL8219815 | 0.77 | THRB (0.61) | THRBHDAC6HDAC1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007140982-A1 | SUBSTITUTED BENZOXAZOLES | BAYER HEALTHCARE AG (DE) | 2007-12-13 | — | — | WO | disclosed |