Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8226183 | 0.94 | THRB (0.66) | THRBHDAC1NPC1PDK1HDAC6 | |
| SCHEMBL8231039 | 0.84 | THRB (0.56) | THRBALDH1A1 | |
| SCHEMBL8220976 | 0.83 | THRB (0.52) | THRBHDAC1NPC1PDK1HDAC6 | |
| SCHEMBL8225281 | 0.81 | THRB (0.56) | THRBHDAC1NPC1PDK1HDAC6 | |
| SCHEMBL8219815 | 0.81 | THRB (0.61) | THRBHDAC1NPC1HDAC6 | |
| SCHEMBL8228596 | 0.81 | THRB (0.65) | THRBHDAC1NPC1HDAC6 | |
| SCHEMBL8229490 | 0.80 | THRB (0.55) | THRBHDAC1NPC1PDK1HDAC6 | |
| SCHEMBL8229319 | 0.80 | THRB (0.55) | THRBHDAC1NPC1HDAC6 | |
| SCHEMBL8225217 | 0.79 | THRB (0.52) | THRBHDAC1NPC1HDAC6 | |
| SCHEMBL8228205 | 0.79 | THRB (0.65) | THRBHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007140982-A1 | SUBSTITUTED BENZOXAZOLES | BAYER HEALTHCARE AG (DE) | 2007-12-13 | — | — | WO | disclosed |