Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.45 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497818 | 0.83 | SIGMAR1 (0.55) | SIGMAR1MAPTKMT2APOLBMEN1 | |
| SCHEMBL3556483 | 0.83 | SIGMAR1 (0.55) | SIGMAR1MAPTKMT2APOLBMEN1 | |
| SCHEMBL497817 | 0.83 | SIGMAR1 (0.55) | SIGMAR1MAPTKMT2APOLBMEN1 | |
| SCHEMBL6334900 | 0.83 | SIGMAR1 (0.47) | SIGMAR1MAPTKMT2APOLBMEN1 | |
| SCHEMBL6710996 | 0.81 | SIGMAR1 (0.53) | SIGMAR1MAPTKMT2APOLBMEN1 | |
| Hydrochloric Acid SCHEMBL1026469 | 0.81 | SIGMAR1 (0.53) | SIGMAR1MAPTKMT2APOLBMEN1 | |
| Hydrochloric Acid SCHEMBL29221566 | 0.81 | SIGMAR1 (0.53) | SIGMAR1MAPTKMT2APOLBMEN1 | |
| SCHEMBL7710834 | 0.81 | SIGMAR1 (0.53) | SIGMAR1MAPTKMT2APOLBMEN1 | |
| Hydrochloric Acid SCHEMBL7827035 | 0.81 | SIGMAR1 (0.53) | SIGMAR1MAPTKMT2APOLBMEN1 | |
| SCHEMBL17029842 | 0.81 | POLB (0.45) | SIGMAR1KMT2APOLBMEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010985-A2 | PHOSPHORUS DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | MERCK & CO., INC. (US) | 2008-01-24 | — | — | WO | disclosed |