Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ACP3 | P15309 | 3/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7496252 | 0.84 | ALDH1A1 (0.53) | SIGMAR1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL8220982 | 0.83 | SIGMAR1 (0.50) | SIGMAR1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL20640584 | 0.81 | SMN1; SMN2 (0.50) | SIGMAR1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL26640075 | 0.75 | SIGMAR1 (0.49) | SIGMAR1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL26640069 | 0.75 | SIGMAR1 (0.49) | SIGMAR1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL10891463 | 0.75 | SLC1A3 (0.50) | SIGMAR1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL17925943 | 0.74 | SIGMAR1 (0.57) | SIGMAR1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL2472408 | 0.74 | SIGMAR1 (0.57) | SIGMAR1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL19069296 | 0.74 | SIGMAR1 (0.61) | SIGMAR1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL10284202 | 0.74 | SIGMAR1 (0.61) | SIGMAR1KMT2AALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050137145-A1 | Metabolites of 1-dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol and their use in the treatment of urinary incontinence | GRUENENTHAL GMBH (DE) | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137145-A1 | Metabolites of 1-dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol and their use in the treatment of urinary incontinence | PNMT, HNMT, PDE3A | SIGMAR1 1539/4885KMT2A 1655/4885ALDH1A1 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.