Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14294658 | 0.84 | KMT2A (0.44) | KMT2AMEN1MAPTDCTPP1ALDH1A1 | |
| SCHEMBL8223557 | 0.81 | ESR1 (0.49) | KMT2AMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL14271022 | 0.81 | KMT2A (0.42) | KMT2AMEN1MAPTDCTPP1ALDH1A1 | |
| SCHEMBL8212225 | 0.80 | MAPT (0.42) | KMT2AMEN1MAPTLMNANPSR1 | |
| SCHEMBL8218208 | 0.75 | KDM4E (0.61) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL3277198 | 0.73 | KDM4E (0.51) | KMT2AMEN1GAAKDM4EUSP2 | |
| SCHEMBL14298815 | 0.73 | MEN1 (0.45) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL8221922 | 0.69 | GABRA1 (0.46) | KMT2AMEN1ALDH1A1GAAADORA1 | |
| SCHEMBL14790653 | 0.67 | LMNA (0.36) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL8213977 | 0.67 | LMNA (0.51) | KMT2AMEN1MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021871-A2 | TRIAZOLYL ACYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |