Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL822133 | 0.98 | LMNA (0.47) | NPC1RAB9ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL821833 | 0.93 | LMNA (0.48) | NPC1RAB9ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL28408919 | 0.87 | LMNA (0.43) | NPC1RAB9ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL821932 | 0.86 | LMNA (0.52) | SMN1; SMN2LMNAMAPK1CES2CES1 | |
| SCHEMBL26611026 | 0.86 | LMNA (0.52) | SMN1; SMN2LMNAMAPK1CES2CES1 | |
| SCHEMBL9093917 | 0.85 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL2050163 | 0.85 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL9093913 | 0.85 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL19215891 | 0.85 | SMN1; SMN2 (0.45) | NPC1RAB9ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL2050162 | 0.85 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110287102-A1 | CHAIN EXTENDERS | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287102-A1 | CHAIN EXTENDERS | UMPS, PUF60, SMCHD1 | NPC1 3411/4885RAB9A 4626/4885SMN1; SMN2 421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.